Sugi Predict

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SCHEMBL25200370

SCHEMBL25200370

CCCCCCCOc1ccc(C(=O)Nc2ccc(C(=O)/C=C/c3ccc(N(C)CCO)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 14/20 0.54
▸ ACHE P22303 12/20 0.54
▸ ABCG2 Q9UNQ0 1/20 0.53
▸ KDM4E B2RXH2 1/20 0.53
▸ ALDH1A1 P00352 1/20 0.53
▸ MAPT P10636 1/20 0.53
▸ TSHR P16473 1/20 0.53
▸ RAB9A P51151 1/20 0.53
▸ MCL1 Q07820 1/20 0.53
▸ HSD17B10 Q99714 1/20 0.53
▸ SAE1 Q9UBE0 1/20 0.51
▸ UBA2 Q9UBT2 1/20 0.51
▸ MAOB P27338 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15218178 0.97 ABCG2 (0.56) BCHEACHEABCG2KDM4EALDH1A1
SCHEMBL15218313 0.87 KDM4E (0.51) KDM4ERAB9A
SCHEMBL15218118 0.87 KDM4E (0.51) KDM4ERAB9A
SCHEMBL15218193 0.86 KDM4E (0.52) KDM4ERAB9A
SCHEMBL15218419 0.86 MAOB (0.60) BCHEKDM4EALDH1A1MAPTRAB9A
SCHEMBL15218420 0.85 KDM4E (0.55) KDM4EALDH1A1MAPTRAB9AMAOB
SCHEMBL15218415 0.83 TUBB4A (0.69) ALDH1A1MAPTRAB9AMAOB
SCHEMBL15218358 0.83 TUBB4A (0.69) ALDH1A1MAPTRAB9AMAOB
SCHEMBL15218339 0.83 TUBB4A (0.69) ALDH1A1MAPTRAB9AMAOB
SCHEMBL15218188 0.83 RAB9A (0.47) KDM4EALDH1A1MAPTRAB9AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B BCHE 588/4885ACHE 806/4885ABCG2 1606/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 BCHE 465/4885ACHE 656/4885ABCG2 3622/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 BCHE 465/4885ACHE 656/4885ABCG2 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.