SCHEMBL7308126

SCHEMBL7308126

O=C(/C=C/c1ccc(Cl)c(Cl)c1)c1ccc(O)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.69
F3 P13726 2/20 0.69
CXCL12 P48061 3/20 0.69
MAOB P27338 3/20 0.69
MAPT P10636 4/20 0.68
RAB9A P51151 4/20 0.68
NPSR1 Q6W5P4 2/20 0.68
MITF O75030 1/20 0.68
RECQL P46063 1/20 0.68
GUSB P08236 1/20 0.67
CYP3A4 P08684 3/20 0.59
CYP1B1 Q16678 2/20 0.59
MAOA P21397 2/20 0.59
CYP1A1 P04798 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP2D6 P10635 1/20 0.59
ESR1 P03372 1/20 0.59
ESR2 Q92731 1/20 0.59
POLB P06746 1/20 0.59
HSPD1 P10809 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25199743 1.00 PTGS2 (0.69) PTGS2F3CXCL12MAOBMAPT
SCHEMBL31233368 1.00 PTGS2 (0.69) PTGS2F3CXCL12MAOBMAPT
SCHEMBL7304255 1.00 PTGS2 (0.69) PTGS2F3CXCL12MAOBMAPT
SCHEMBL30383198 1.00 PTGS2 (0.69) PTGS2F3CXCL12MAOBMAPT
SCHEMBL7306057 0.90 F3 (0.69) PTGS2F3CXCL12MAOBMAPT
SCHEMBL7312933 0.90 F3 (0.69) PTGS2F3CXCL12MAOBMAPT
SCHEMBL25200404 0.89 BACE1 (0.68) F3CXCL12MAOBMAPTRAB9A
SCHEMBL30383358 0.89 BACE1 (0.68) F3CXCL12MAOBMAPTRAB9A
SCHEMBL25198501 0.89 BACE1 (0.68) F3CXCL12MAOBMAPTRAB9A
SCHEMBL1225523 0.89 PTGS2 (0.71) PTGS2CXCL12MAOBCYP3A4CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
CN-117304033-A Caffeic acid derivative and preparation method thereof, pharmaceutical composition and application 中国医学科学院药物研究所 2023-12-29 CN disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
WO-2008016738-A2 ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-02-07 WO disclosed
EP-0947494-A1 Derivatives of phenoxy acetic acid and phenoxymethyltetrazole having antitumor activity F. HOFFMANN-LA ROCHE AG (CH) 1999-10-06 EP disclosed
EP-0947511-A1 Derivatives of phenoxy acetic acid and of phenoxymethyl tetrazole having antitumor activity F. HOFFMANN-LA ROCHE AG (CH) 1999-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B PTGS2 704/4885F3 5/4885CXCL12 399/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 PTGS2 330/4885F3 11/4885CXCL12 287/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 PTGS2 330/4885F3 11/4885CXCL12 287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.