SCHEMBL25200569

SCHEMBL25200569

CCCc1c(OCCCOc2ccc(C(=O)/C=C/c3ccccc3)cc2)ccc(C(C)=O)c1O

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GRM2 Q14416 4/20 0.68
▸ PPARG P37231 2/20 0.66
▸ PPARD Q03181 2/20 0.66
▸ PPARA Q07869 2/20 0.66
▸ LMNA P02545 1/20 0.66
▸ CYP1A2 P05177 1/20 0.66
▸ MAPT P10636 1/20 0.66
▸ CYP2C9 P11712 1/20 0.66
▸ NFKB1 P19838 1/20 0.66
▸ BLM P54132 1/20 0.66
▸ CYSLTR2 Q9NS75 7/20 0.59
▸ CYSLTR1 Q9Y271 7/20 0.59
▸ BCHE P06276 6/20 0.56
▸ ACHE P22303 5/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25203622 0.96 GRM2 (0.66) GRM2PPARGPPARDPPARALMNA
SCHEMBL11043538 0.87 PPARG (0.72) GRM2PPARGPPARDPPARALMNA
SCHEMBL11043542 0.87 PPARG (0.72) GRM2PPARGPPARDPPARALMNA
SCHEMBL5032476 0.85 GRM2 (0.72) GRM2PPARGPPARDPPARALMNA
SCHEMBL5032472 0.85 GRM2 (0.72) GRM2PPARGPPARDPPARALMNA
SCHEMBL10744397 0.84 GRM2 (0.95) GRM2PPARGPPARDPPARALMNA
SCHEMBL11047154 0.82 CYSLTR2 (0.71) GRM2PPARGPPARDPPARALMNA
SCHEMBL11047150 0.82 CYSLTR2 (0.71) GRM2PPARGPPARDPPARALMNA
SCHEMBL9043028 0.82 GRM2 (0.80) GRM2PPARGPPARDPPARALMNA
Propionic Acid SCHEMBL11043565 0.82 PPARG (0.79) GRM2PPARGPPARDPPARALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B GRM2 4882/4885PPARG 4105/4885PPARD 2675/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 GRM2 4883/4885PPARG 3395/4885PPARD 3892/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 GRM2 4883/4885PPARG 3395/4885PPARD 3892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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