Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25215123 | 0.92 | FEN1 (0.43) | KDM4EMEN1LMNAHPGDMAPK1 | |
| SCHEMBL25235921 | 0.92 | KDM4E (0.44) | KDM4EMEN1LMNACYP2C9HPGD | |
| SCHEMBL25199917 | 0.90 | KDM4E (0.42) | KDM4EMEN1KMT2ACA1CA2 | |
| SCHEMBL25193550 | 0.87 | PTGES (0.39) | KDM4E | |
| SCHEMBL25197804 | 0.86 | NR4A2 (0.48) | CA9 | |
| SCHEMBL25209836 | 0.85 | LMNA (0.49) | KDM4EMEN1LMNACYP2C9HPGD | |
| SCHEMBL25235907 | 0.84 | ALDH1A1 (0.42) | KDM4EMEN1HPGDKMT2A | |
| SCHEMBL25199951 | 0.84 | LMNA (0.48) | KDM4EMEN1LMNACYP2C9HPGD | |
| SCHEMBL25196072 | 0.81 | KDM4E (0.46) | KDM4EMEN1LMNACYP2C9HPGD | |
| SCHEMBL25209824 | 0.81 | KDM4E (0.45) | KDM4ECLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271925-A1 | NOVEL TNF ACTIVITY INHIBITOR COMPOUND, AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ILAb Co., Ltd. (KR) | 2023-08-31 | — | — | US | claimed |
| EP-4180423-A1 | NOVEL TNF ACTIVITY INHIBITOR COMPOUND, AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ILAb Co., Ltd. (KR) | 2023-05-17 | — | — | EP | claimed |
| US-20230271925-A1 | NOVEL TNF ACTIVITY INHIBITOR COMPOUND, AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ILAb Co., Ltd. (KR) | 2023-08-31 | — | — | US | disclosed |
| EP-4180423-A1 | NOVEL TNF ACTIVITY INHIBITOR COMPOUND, AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ILAb Co., Ltd. (KR) | 2023-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271925-A1 | NOVEL TNF ACTIVITY INHIBITOR COMPOUND, AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TNF, NFKBIA, TNFRSF9 | KDM4E 2857/4885MEN1 3757/4885LMNA 3926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.