SCHEMBL25201162

SCHEMBL25201162

CS(=O)(=O)Nc1ccc(C(=O)/C=C\c2cccc(O)c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
P4HB P07237 7/20 0.67
LMNA P02545 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
NPC1 O15118 1/20 0.52
MAPT P10636 1/20 0.52
RAB9A P51151 1/20 0.52
MMP1 P03956 2/20 0.51
MMP2 P08253 2/20 0.51
MMP9 P14780 2/20 0.51
CYP1A1 P04798 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP1B1 Q16678 1/20 0.51
MAOB P27338 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384379 1.00 P4HB (0.67) P4HBLMNASMN1; SMN2NPSR1NPC1
SCHEMBL25198564 1.00 P4HB (0.67) P4HBLMNASMN1; SMN2NPSR1NPC1
SCHEMBL31233214 1.00 P4HB (0.67) P4HBLMNASMN1; SMN2NPSR1NPC1
SCHEMBL25211862 1.00 P4HB (0.67) P4HBLMNASMN1; SMN2NPSR1NPC1
SCHEMBL25199621 0.88 P4HB (0.64) P4HBLMNASMN1; SMN2NPSR1NPC1
SCHEMBL31233059 0.88 P4HB (0.64) P4HBLMNASMN1; SMN2NPSR1NPC1
SCHEMBL30383625 0.88 P4HB (0.64) P4HBLMNASMN1; SMN2NPSR1NPC1
SCHEMBL25210418 0.88 P4HB (0.64) P4HBLMNASMN1; SMN2NPSR1NPC1
SCHEMBL25190651 0.88 P4HB (0.64) P4HBLMNASMN1; SMN2NPSR1NPC1
SCHEMBL3484452 0.85 P4HB (0.71) P4HBLMNASMN1; SMN2NPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B P4HB 552/4885LMNA 1180/4885SMN1; SMN2 3415/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 P4HB 469/4885LMNA 1817/4885SMN1; SMN2 4161/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 P4HB 469/4885LMNA 1817/4885SMN1; SMN2 4161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.