SCHEMBL25210418

SCHEMBL25210418

CCS(=O)(=O)Nc1ccc(C(=O)C=Cc2cccc(O)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
P4HB P07237 7/20 0.64
NPSR1 Q6W5P4 2/20 0.53
LMNA P02545 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
MAPT P10636 2/20 0.50
RAB9A P51151 2/20 0.50
HPGD P15428 1/20 0.50
NPC1 O15118 1/20 0.50
BCHE P06276 1/20 0.49
MMP1 P03956 1/20 0.49
MMP2 P08253 1/20 0.49
MMP9 P14780 1/20 0.49
CYP1A1 P04798 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP1B1 Q16678 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383625 1.00 P4HB (0.64) P4HBNPSR1LMNASMN1; SMN2MAPT
SCHEMBL25190651 1.00 P4HB (0.64) P4HBNPSR1LMNASMN1; SMN2MAPT
SCHEMBL25199621 1.00 P4HB (0.64) P4HBNPSR1LMNASMN1; SMN2MAPT
SCHEMBL31233059 1.00 P4HB (0.64) P4HBNPSR1LMNASMN1; SMN2MAPT
SCHEMBL25198564 0.88 P4HB (0.67) P4HBNPSR1LMNASMN1; SMN2MAPT
SCHEMBL31233214 0.88 P4HB (0.67) P4HBNPSR1LMNASMN1; SMN2MAPT
SCHEMBL30384379 0.88 P4HB (0.67) P4HBNPSR1LMNASMN1; SMN2MAPT
SCHEMBL25211862 0.88 P4HB (0.67) P4HBNPSR1LMNASMN1; SMN2MAPT
SCHEMBL25201162 0.88 P4HB (0.67) P4HBNPSR1LMNASMN1; SMN2MAPT
SCHEMBL3484452 0.83 P4HB (0.71) P4HBNPSR1LMNASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 P4HB 469/4885NPSR1 4282/4885LMNA 1817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.