Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 7/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.52 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.52 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.52 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.52 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25187050 | 0.95 | DRD2 (0.54) | DRD4DRD2ACKR3HTR3EHTR3B | |
| SCHEMBL25187641 | 0.90 | HPGDS (0.49) | ACKR3HTR3EHTR3BCHRNA7HTR3A | |
| SCHEMBL25194856 | 0.87 | DCLK1 (0.49) | PRKAA1ACKR3HTR3EHTR3BCHRNA7 | |
| SCHEMBL25193312 | 0.84 | HTR3E (0.46) | PRKAA1ACKR3HTR3EHTR3BCHRNA7 | |
| SCHEMBL25203120 | 0.84 | TLR9 (0.51) | ACKR3HTR3EHTR3BCHRNA7HTR3A | |
| SCHEMBL25187069 | 0.84 | HRH2 (0.44) | ACKR3HTR3EHTR3BCHRNA7HTR3A | |
| SCHEMBL25187486 | 0.82 | PRKAA2 (0.46) | PRKAA2ACKR3 | |
| SCHEMBL25192994 | 0.82 | HRH2 (0.54) | ACKR3 | |
| SCHEMBL25187055 | 0.81 | TLR9 (0.43) | ACKR3HTR3EHTR3BCHRNA7HTR3A | |
| SCHEMBL25187465 | 0.81 | MEN1 (0.43) | ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023089052-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR DISEASES OF THE CNS | Samsara Therapeutics Inc. (US) | 2023-05-25 | — | — | WO | claimed |