SCHEMBL25201636

SCHEMBL25201636

Cc1ccc(C(=O)/C=C/c2ccc(F)cc2)c(O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 2/20 0.69
▸ MAOB P27338 3/20 0.66
▸ MAOA P21397 2/20 0.64
▸ P4HB P07237 2/20 0.61
▸ MAPT P10636 4/20 0.61
▸ KMT2A Q03164 2/20 0.61
▸ NPC1 O15118 1/20 0.61
▸ RAB9A P51151 1/20 0.61
▸ BACE1 P56817 3/20 0.59
▸ CYP3A4 P08684 2/20 0.59
▸ CYP2C9 P11712 2/20 0.59
▸ NFKB1 P19838 2/20 0.59
▸ CYP2C19 P33261 2/20 0.59
▸ NPSR1 Q6W5P4 2/20 0.59
▸ MEN1 O00255 1/20 0.59
▸ GMNN O75496 1/20 0.59
▸ LMNA P02545 1/20 0.59
▸ ESR1 P03372 1/20 0.59
▸ MMP1 P03956 1/20 0.59
▸ GBA1 P04062 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25198771 0.91 MAOB (0.74) CTSLMAOBMAOAP4HBMAPT
SCHEMBL25191023 0.88 MAPT (0.77) MAOBMAOAP4HBMAPTKMT2A
SCHEMBL25193705 0.85 MAOB (0.74) MAOBMAOAP4HBMAPTKMT2A
SCHEMBL25218083 0.85 MAOB (0.74) MAOBMAOAP4HBMAPTKMT2A
SCHEMBL25202940 0.85 NFE2L2 (0.75) P4HBMAPTKMT2ANPC1RAB9A
SCHEMBL11683750 0.85 NFE2L2 (0.75) P4HBMAPTKMT2ANPC1RAB9A
SCHEMBL11683753 0.85 NFE2L2 (0.75) P4HBMAPTKMT2ANPC1RAB9A
SCHEMBL23303982 0.85 CYP3A4 (0.82) CTSLMAOBMAOAP4HBMAPT
SCHEMBL25195306 0.85 CYP3A4 (0.82) CTSLMAOBMAOAP4HBMAPT
SCHEMBL30383838 0.85 NFE2L2 (0.75) P4HBMAPTKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CTSL 357/4885MAOB 1004/4885MAOA 1902/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CTSL 310/4885MAOB 2435/4885MAOA 3145/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CTSL 310/4885MAOB 2435/4885MAOA 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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