Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25202940 | 1.00 | NFE2L2 (0.75) | NFE2L2MAPTKMT2ACYP3A4ALDH1A1 | |
| SCHEMBL30383838 | 1.00 | NFE2L2 (0.75) | NFE2L2MAPTKMT2ACYP3A4ALDH1A1 | |
| SCHEMBL11683753 | 1.00 | NFE2L2 (0.75) | NFE2L2MAPTKMT2ACYP3A4ALDH1A1 | |
| SCHEMBL5450210 | 0.89 | GUSB (0.74) | NFE2L2MAPTCYP2C19BCHEGUSB | |
| SCHEMBL5450213 | 0.89 | GUSB (0.74) | NFE2L2MAPTCYP2C19BCHEGUSB | |
| SCHEMBL25191023 | 0.88 | MAPT (0.77) | MAPTKMT2ACYP3A4ALDH1A1MEN1 | |
| SCHEMBL25191208 | 0.87 | APP (0.70) | NFE2L2MAPTKMT2ACYP3A4ALDH1A1 | |
| SCHEMBL25203017 | 0.87 | APP (0.70) | NFE2L2MAPTKMT2ACYP3A4ALDH1A1 | |
| SCHEMBL25194260 | 0.87 | MAOA (0.69) | NFE2L2MAPTKMT2ACYP3A4ALDH1A1 | |
| SCHEMBL25264972 | 0.87 | MAOA (0.69) | NFE2L2MAPTKMT2ACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170326045-A1 | COSMETIC COMPOSITION COMPRISING A SYNTHETIC PHYLLOSILICATE AND A POLYOL AND/OR A UV FILTER | L'OREAL (FR) | 2017-11-16 | — | — | US | disclosed |
| US-20170304658-A1 | GEL/GEL COMPOSITION COMPRISING A UV-SCREENING AGENT | L'OREAL (FR) | 2017-10-26 | — | — | US | disclosed |
| US-20160374997-A1 | ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2016-12-29 | — | — | US | disclosed |
| US-20160220510-A1 | ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2016-08-04 | — | — | US | disclosed |
| US-20160220510-A1 | ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2016-08-04 | — | — | US | disclosed |
| US-20150190320-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES | L'OREAL (FR) | 2015-07-09 | — | — | US | disclosed |
| US-20150157539-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES | L'OREAL (FR) | 2015-06-11 | — | — | US | disclosed |
| US-4035395-A | Process for the preparation of ketones | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-12 | — | — | US | disclosed |
| US-4014889-A | Process for preparing ketones | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160374997-A1 | ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS | AARS1, EPRS1, EEF1G | NFE2L2 2563/4885MAPT 1595/4885KMT2A 2096/4885 |
| US-20160220510-A1 | ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS | AARS1, EPRS1, EEF1G | NFE2L2 2563/4885MAPT 1595/4885KMT2A 2096/4885 |
| US-20170326045-A1 | COSMETIC COMPOSITION COMPRISING A SYNTHETIC PHYLLOSILICATE AND A POLYOL AND/OR A UV FILTER | PUF60, POLR1C, DPM1 | NFE2L2 1872/4885MAPT 938/4885KMT2A 1673/4885 |
| US-20150157539-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES | MITF, RAB5IF, TYR | NFE2L2 4376/4885MAPT 922/4885KMT2A 3148/4885 |
| US-20170304658-A1 | GEL/GEL COMPOSITION COMPRISING A UV-SCREENING AGENT | CUTA, KRT18, APOL1 | NFE2L2 3031/4885MAPT 369/4885KMT2A 2296/4885 |
| US-20150190320-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES | XPA, ERCC1, ERCC4 | NFE2L2 2283/4885MAPT 2352/4885KMT2A 3290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.