SCHEMBL25201964

SCHEMBL25201964

COc1ccc(C=CC(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)cc1O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.77
▸ MAPT P10636 7/20 0.77
▸ KMT2A Q03164 7/20 0.77
▸ MEN1 O00255 5/20 0.77
▸ POLB P06746 4/20 0.77
▸ GAA P10253 4/20 0.77
▸ HPGD P15428 4/20 0.77
▸ KDM4E B2RXH2 4/20 0.77
▸ LMNA P02545 3/20 0.77
▸ MAPK1 P28482 3/20 0.77
▸ USP2 O75604 2/20 0.77
▸ HTT P42858 2/20 0.77
▸ JAK2 O60674 1/20 0.77
▸ THRB P10828 1/20 0.77
▸ ALOX12 P18054 1/20 0.77
▸ L3MBTL1 Q9Y468 1/20 0.77
▸ NPSR1 Q6W5P4 1/20 0.59
▸ SMN1; SMN2 Q16637 2/20 0.58
▸ TUBB4A P04350 1/20 0.56
▸ TUBB P07437 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25202505 1.00 ALDH1A1 (0.77) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL30382769 1.00 ALDH1A1 (0.77) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL30383699 1.00 ALDH1A1 (0.77) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL25197128 0.99 ALDH1A1 (0.74) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL31233324 0.99 ALDH1A1 (0.74) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL25235112 0.99 ALDH1A1 (0.74) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL25205645 0.92 ALDH1A1 (0.77) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL30383832 0.90 ALDH1A1 (0.61) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL25199729 0.90 ALDH1A1 (0.61) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL25216325 0.87 MAPT (1.00) ALDH1A1MAPTKMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ALDH1A1 3285/4885MAPT 3297/4885KMT2A 2792/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ALDH1A1 3081/4885MAPT 3512/4885KMT2A 3188/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ALDH1A1 3081/4885MAPT 3512/4885KMT2A 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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