Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 16/20 | 0.48 |
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | FAP | Q12884 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30406700 | 1.00 | CCR2 (0.48) | CCR2PREPDPP4FAPTAS1R3 | |
| SCHEMBL30407017 | 0.97 | CCR2 (0.49) | CCR2ALDH1A1POLB | |
| SCHEMBL25190893 | 0.97 | CCR2 (0.49) | CCR2ALDH1A1POLB | |
| SCHEMBL25221229 | 0.86 | CCR2 (0.42) | CCR2 | |
| SCHEMBL6358011 | 0.85 | CCR2 (0.49) | CCR2PREPDPP4TAS1R3TAS1R1 | |
| SCHEMBL18544383 | 0.81 | CCR2 (0.55) | CCR2PREPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL18544775 | 0.81 | CCR2 (0.52) | CCR2PREPDPP4FAPALDH1A1 | |
| SCHEMBL25184672 | 0.81 | ACKR3 (0.43) | FAP | |
| SCHEMBL25548080 | 0.80 | CCR2 (0.48) | CCR2 | |
| SCHEMBL25199498 | 0.80 | ACKR3 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |