Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 4/20 | 0.38 |
| ▸ | BRAF | P15056 | 4/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25190893 | 0.83 | CCR2 (0.49) | — | |
| SCHEMBL30407017 | 0.83 | CCR2 (0.49) | — | |
| SCHEMBL25202249 | 0.81 | CCR2 (0.48) | FAP | |
| SCHEMBL30406700 | 0.81 | CCR2 (0.48) | FAP | |
| SCHEMBL25199498 | 0.80 | ACKR3 (0.46) | ACKR3 | |
| SCHEMBL25184669 | 0.79 | TRPA1 (0.40) | ACKR3DDR1TRPA1FAPGLS | |
| Hydrochloric Acid SCHEMBL25191497 | 0.79 | TRPA1 (0.40) | ACKR3DDR1TRPA1FAPGLS | |
| SCHEMBL25202245 | 0.78 | DDR1 (0.52) | ACKR3DDR1TRPA1GLSRAF1 | |
| SCHEMBL25221229 | 0.74 | CCR2 (0.42) | — | |
| SCHEMBL25552436 | 0.71 | DDR1 (0.52) | ACKR3DDR1TRPA1GLSRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |