Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 19/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25190893 | 0.82 | CCR2 (0.49) | — | |
| SCHEMBL30407017 | 0.82 | CCR2 (0.49) | — | |
| SCHEMBL25184672 | 0.80 | ACKR3 (0.43) | ACKR3 | |
| SCHEMBL25202249 | 0.80 | CCR2 (0.48) | — | |
| SCHEMBL30406700 | 0.80 | CCR2 (0.48) | — | |
| SCHEMBL25193593 | 0.79 | P2RX7 (0.46) | ACKR3P2RX7 | |
| Hydrochloric Acid SCHEMBL25188592 | 0.78 | P2RX7 (0.45) | ACKR3P2RX7 | |
| SCHEMBL25221229 | 0.73 | CCR2 (0.42) | — | |
| SCHEMBL25188278 | 0.69 | P2RX7 (0.68) | ACKR3P2RX7 | |
| SCHEMBL27157359 | 0.69 | ACKR3 (0.47) | ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |