SCHEMBL25202467

SCHEMBL25202467

CC(C)OC(=O)C(C)(C)Oc1ccc(/C=C/C(=O)c2ccc(Cl)cc2O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 7/20 0.57
MAOB P27338 6/20 0.57
LMNA P02545 4/20 0.54
MAPT P10636 4/20 0.54
MEN1 O00255 3/20 0.54
CYP3A4 P08684 3/20 0.54
MAPK1 P28482 3/20 0.54
KMT2A Q03164 3/20 0.54
PPARA Q07869 2/20 0.54
CYP2C19 P33261 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
HPGD P15428 2/20 0.54
ACHE P22303 2/20 0.54
ATM Q13315 2/20 0.54
USP2 O75604 1/20 0.54
ABCB11 O95342 1/20 0.54
CYP1A2 P05177 1/20 0.54
ADORA3 P0DMS8 1/20 0.54
CYP2C9 P11712 1/20 0.54
ADRB3 P13945 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25207753 0.87 MAOB (0.60) ABCG2MAOBLMNAMAPTMEN1
SCHEMBL814705 0.86 MAOB (0.63) ABCG2MAOBLMNAMAPTMEN1
SCHEMBL25199613 0.86 PPARA (0.67) ABCG2MAOBLMNAMAPTMEN1
SCHEMBL8752262 0.86 PPARA (0.67) ABCG2MAOBLMNAMAPTMEN1
SCHEMBL814608 0.85 MAOB (0.60) ABCG2MAOBMAPTMEN1CYP3A4
SCHEMBL25193894 0.85 MAOB (0.60) ABCG2MAOBMAPTMEN1CYP3A4
SCHEMBL498900 0.82 CXCL12 (0.42) ABCG2MAOBLMNAMAPTMEN1
SCHEMBL815468 0.79 MAOB (0.70) ABCG2MAOBLMNAMAPTMEN1
SCHEMBL25216289 0.79 MAOB (0.70) ABCG2MAOBLMNAMAPTMEN1
SCHEMBL25195950 0.78 MAOB (0.85) ABCG2MAOBLMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885MAOB 1004/4885LMNA 1180/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAOB 2435/4885LMNA 1817/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAOB 2435/4885LMNA 1817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.