SCHEMBL25199613

SCHEMBL25199613

CC(C)(Oc1ccc(C=CC(=O)c2ccc(Cl)cc2O)cc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.67
MAOB P27338 6/20 0.63
ABCG2 Q9UNQ0 6/20 0.63
MAOA P21397 2/20 0.56
MAPT P10636 4/20 0.55
MEN1 O00255 3/20 0.55
CYP3A4 P08684 3/20 0.55
KMT2A Q03164 3/20 0.55
LMNA P02545 3/20 0.55
CYP2C19 P33261 2/20 0.55
MAPK1 P28482 2/20 0.55
APP P05067 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
NPC1 O15118 1/20 0.53
RECQL P46063 1/20 0.53
RAB9A P51151 1/20 0.53
ATM Q13315 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8752262 1.00 PPARA (0.67) PPARAMAOBABCG2MAOAMAPT
SCHEMBL815468 0.93 MAOB (0.70) PPARAMAOBABCG2MAOAMAPT
SCHEMBL25216289 0.93 MAOB (0.70) PPARAMAOBABCG2MAOAMAPT
SCHEMBL814705 0.91 MAOB (0.63) PPARAMAOBABCG2MAOAMAPT
SCHEMBL25198434 0.88 MEN1 (0.69) PPARAMAOBABCG2MAOAMAPT
SCHEMBL814529 0.88 MEN1 (0.69) PPARAMAOBABCG2MAOAMAPT
SCHEMBL25207753 0.88 MAOB (0.60) PPARAMAOBABCG2MAOAMAPT
SCHEMBL14491085 0.87 CYP3A4 (0.63) PPARAMAOBABCG2MAOAMAPT
SCHEMBL30384412 0.87 CYP3A4 (0.63) PPARAMAOBABCG2MAOAMAPT
SCHEMBL25202467 0.86 ABCG2 (0.57) PPARAMAOBABCG2MAOAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B PPARA 4345/4885MAOB 1004/4885ABCG2 1606/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 PPARA 4095/4885MAOB 2435/4885ABCG2 3622/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 PPARA 4095/4885MAOB 2435/4885ABCG2 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.