Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL25267264 | 1.00 | KEAP1 (0.43) | KEAP1SSTR4SSTR1CHRM1CHRM3 | |
| SCHEMBL25266833 | 0.90 | KEAP1 (0.44) | KEAP1CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL25202810 | 0.90 | KEAP1 (0.44) | KEAP1CHRM1CHRM3CHRM2CHRM4 | |
| Trifluoroacetic Acid SCHEMBL31157790 | 0.77 | L3MBTL1 (0.40) | KEAP1MMP2MMP3MMP9MMP13 | |
| Trifluoroacetic Acid SCHEMBL25210334 | 0.77 | L3MBTL1 (0.40) | KEAP1MMP2MMP3MMP9MMP13 | |
| Trifluoroacetic Acid SCHEMBL30449219 | 0.74 | ITGB3 (0.48) | CHRM1CHRM2CHRM4CYP1A2CYP2C9 | |
| Trifluoroacetic Acid SCHEMBL1678087 | 0.72 | CHRM3 (0.38) | KEAP1SSTR4SSTR1CHRM3CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL1678089 | 0.72 | CHRM3 (0.38) | KEAP1SSTR4SSTR1CHRM3CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL25370260 | 0.72 | CA12 (0.38) | KEAP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL8221682 | 0.71 | CYP1A2 (0.48) | KEAP1CHRM3CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034150-A1 | BTK INHIBITORS | BIOGEN MA INC. | 2025-01-30 | — | — | US | disclosed |
| EP-4429770-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086521-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2023-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034150-A1 | BTK INHIBITORS | BTK, SYK, LYN | KEAP1 1955/4885SSTR4 2779/4885SSTR1 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.