Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25230843 | 0.87 | CHEK1 (0.45) | PTGDR2HTR2CGRM2KDM5ACHEK1 | |
| SCHEMBL25551048 | 0.84 | HTR2C (0.50) | PTGDR2MEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL25217041 | 0.83 | CHEK1 (0.43) | PTGDR2HTR2CPARP1KDM5ACHEK1 | |
| SCHEMBL25552703 | 0.83 | HTR2C (0.52) | PTGDR2MEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL25222071 | 0.82 | KDM5A (0.44) | PTGDR2HTR2CGRM2KDM5ACHEK1 | |
| SCHEMBL25207419 | 0.82 | KDM5A (0.44) | PTGDR2HTR2CGRM2KDM5ACHEK1 | |
| SCHEMBL31370726 | 0.81 | PTGDR2 (0.41) | PTGDR2RAB9AHTR2CCFTRGRM2 | |
| SCHEMBL25203568 | 0.81 | PTGDR2 (0.42) | PTGDR2HTR2CGRM2KDM5A | |
| SCHEMBL25419155 | 0.81 | REN (0.41) | PTGDR2HTR2CGRM2KDM5ACHEK1 | |
| Hydrochloric Acid SCHEMBL25268211 | 0.81 | KDM5A (0.44) | PTGDR2HTR2CGRM2KDM5ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034127-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR DISEASES OF THE CNS | UNIVERSITÉ PARIS CITÉ (FR) | 2025-01-30 | — | — | US | claimed |
| EP-4433162-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR DISEASES OF THE CNS | Samsara Therapeutics Inc. (US) | 2024-09-25 | — | — | EP | claimed |
| CN-118647613-A | Autophagy inducing compounds and uses thereof, in particular for central nervous system diseases | 轮回治疗公司 | 2024-09-13 | — | — | CN | claimed |
| WO-2023089052-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR DISEASES OF THE CNS | Samsara Therapeutics Inc. (US) | 2023-05-25 | — | — | WO | claimed |
| US-20250034127-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR DISEASES OF THE CNS | UNIVERSITÉ PARIS CITÉ (FR) | 2025-01-30 | — | — | US | disclosed |
| EP-4183449-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034127-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF, IN PARTICULAR FOR DISEASES OF THE CNS | SQSTM1, TFEB, BECN1 | PTGDR2 4500/4885MEN1 2940/4885RAB9A 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.