SCHEMBL25206201

SCHEMBL25206201

CC(Oc1ccc(C(=O)/C=C/c2ccc3c(c2)OCCO3)cc1)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.71
RAB9A P51151 4/20 0.71
NPC1 O15118 3/20 0.65
NPSR1 Q6W5P4 2/20 0.63
CXCL12 P48061 1/20 0.62
STAT3 P40763 1/20 0.57
MAOB P27338 3/20 0.56
KDM4E B2RXH2 2/20 0.54
CYP2D6 P10635 2/20 0.53
ALDH1A1 P00352 2/20 0.53
MAOA P21397 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
LMNA P02545 1/20 0.50
CYP1A1 P04798 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP1B1 Q16678 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382692 1.00 MAPT (0.71) MAPTRAB9ANPC1NPSR1CXCL12
SCHEMBL30383880 1.00 MAPT (0.71) MAPTRAB9ANPC1NPSR1CXCL12
SCHEMBL30383560 1.00 MAPT (0.71) MAPTRAB9ANPC1NPSR1CXCL12
SCHEMBL25219586 1.00 MAPT (0.71) MAPTRAB9ANPC1NPSR1CXCL12
SCHEMBL25195188 1.00 MAPT (0.71) MAPTRAB9ANPC1NPSR1CXCL12
SCHEMBL25206200 1.00 MAPT (0.71) MAPTRAB9ANPC1NPSR1CXCL12
SCHEMBL3072232 0.80 PTGS1 (0.58) RAB9ANPC1NPSR1MAOBKDM4E
SCHEMBL25209471 0.80 XDH (0.68) MAPTRAB9ANPC1CXCL12MAOB
SCHEMBL30383570 0.79 PTGS2 (0.58) MAPTCXCL12MAOBALDH1A1MAOA
SCHEMBL25240934 0.79 PTGS2 (0.58) MAPTCXCL12MAOBALDH1A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885RAB9A 480/4885NPC1 1378/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885RAB9A 1327/4885NPC1 1908/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885RAB9A 1327/4885NPC1 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.