SCHEMBL2520769

SCHEMBL2520769

CCO[Si](CCc1ccccc1)(OCC)OC(C)CS

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
MAPT P10636 1/20 0.33
VCP P55072 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2526803 0.85 SMN1; SMN2 (0.33) SMN1; SMN2NPC1RAB9ATDP1SIGMAR1
SCHEMBL25190738 0.85 SMN1; SMN2 (0.34) SMN1; SMN2NPC1RAB9ATDP1SIGMAR1
SCHEMBL1765859 0.85 TDP1 (0.37) SMN1; SMN2NPC1RAB9ATDP1CYP2D6
SCHEMBL28332141 0.81 SMN1; SMN2 (0.33) SMN1; SMN2NPC1RAB9AMAPTTDP1
SCHEMBL107467 0.81 TDP1 (0.43) SMN1; SMN2NPC1RAB9AMAPTTDP1
SCHEMBL2763041 0.77 NPC1 (0.33) SMN1; SMN2NPC1RAB9AMAPTTDP1
SCHEMBL31028386 0.77 SIGMAR1 (0.40) SIGMAR1CYP2D6
SCHEMBL10696910 0.76 TDP1 (0.39) SMN1; SMN2NPC1RAB9AMAPTTDP1
SCHEMBL15063279 0.74 PDE4A (0.35) CYP2D6CYP2C9CYP2C19KMT2A
SCHEMBL15816499 0.74 SIGMAR1 (0.33) SMN1; SMN2SIGMAR1CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1892089-B1 GAS BARRIER LAMINATE, METHOD FOR PRODUCING SAME AND PACKAGE BODY USING SAME KURARAY CO (JP) 2019-05-29 EP disclosed
EP-1690678-B1 GAS BARRIER LAMINATE AND PACKAGED ARTICLE, AND METHOD FOR PRODUCING GAS BARRIER LAMINATE KURARAY CO (JP) 2016-09-14 EP disclosed
US-8039071-B2 Gas barrier layered product and packaging medium, and method for producing gas barrier layered product KURARAY CO., LTD. (JP) 2011-10-18 US disclosed
US-7799396-B2 food packagings; oxygen barrier property independent of humidity; disposability, waterproofing, high transparency, excellent mechanical properties; neutralize a hydrolyzed and condensed product of tetramethoxysilane, 3-mercaptopropyltrimethoxysilane, and titanium tetraisopropoxide, polyacrylic acid KURARAY CO., LTD. (JP) 2010-09-21 US disclosed
US-20100209639-A1 GAS BARRIER LAYERED PRODUCT AND PACKAGING MEDIUM, AND METHOD FOR PRODUCING GAS BARRIER LAYERED PRODUCT KURARAY CO. LTD. (JP) 2010-08-19 US disclosed
US-7763335-B2 Gas barrier layered product and packaging medium, and method for producing gas barrier layered product KURARAY CO., LTD. (JP) 2010-07-27 US disclosed
US-20090030126-A1 food packagings; oxygen barrier property independent of humidity; disposability, waterproofing, high transparency, excellent mechanical properties; neutralize a hydrolyzed and condensed product of tetramethoxysilane, 3-mercaptopropyltrimethoxysilane, and titanium tetraisopropoxide, polyacrylic acid KURARAY CO., LTD. (JP) 2009-01-29 US disclosed
EP-1892089-A1 GAS BARRIER LAMINATE, METHOD FOR PRODUCING SAME AND PACKAGE BODY USING SAME Kuraray Co., Ltd., Kurashiki Plant (JP) 2008-02-27 EP disclosed
US-20070111005-A1 Gas barrier laminate and packaged article, and method for producing gas barrier laminate KURARAY CO., LTD. (JP) 2007-05-17 US disclosed
EP-1690678-A1 GAS BARRIER LAMINATE AND PACKAGED ARTICLE, AND METHOD FOR PRODUCING GAS BARRIER LAMINATE KURARAY CO., LTD. (JP) 2006-08-16 EP disclosed