SCHEMBL1765859

SCHEMBL1765859

CCO[Si](CCc1ccccc1)(OCC)OC(C)O

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TRPA1 O75762 1/20 0.37
KMT2A Q03164 3/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
TSHR P16473 3/20 0.35
MEN1 O00255 2/20 0.35
HPGD P15428 2/20 0.35
CYP3A4 P08684 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
EPHX2 P34913 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2520769 0.85 SMN1; SMN2 (0.33) TDP1SMN1; SMN2KMT2ACYP2D6CYP2C9
SCHEMBL25190738 0.84 SMN1; SMN2 (0.34) TDP1SMN1; SMN2KMT2ACYP2D6CYP2C9
SCHEMBL28332141 0.83 SMN1; SMN2 (0.33) TDP1SMN1; SMN2KMT2ACYP2D6CYP2C9
SCHEMBL107467 0.83 TDP1 (0.43) TDP1SMN1; SMN2RAB9ANPC1HPGD
SCHEMBL2526803 0.82 SMN1; SMN2 (0.33) TDP1SMN1; SMN2KMT2ACYP2D6CYP2C9
SCHEMBL28452315 0.80 TRPA1 (0.36) SMN1; SMN2TRPA1KMT2ATSHRMEN1
SCHEMBL2763041 0.80 NPC1 (0.33) TDP1SMN1; SMN2KMT2ACYP2D6CYP2C9
SCHEMBL10696910 0.78 TDP1 (0.39) TDP1SMN1; SMN2CYP2D6CYP2C9CYP2C19
SCHEMBL28192360 0.76 HTR2A (0.38) KMT2ACYP2D6CYP2C9CYP2C19EPHX2
SCHEMBL28065352 0.76 RAB9A (0.38) TDP1SMN1; SMN2KMT2ACYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10474032-B2 Coating compositions ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2019-11-12 US disclosed
US-9437431-B2 Electronic device manufacture ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2016-09-06 US disclosed
EP-1720075-B1 Coating compositions ROHM & HAAS ELECT MAT (US) 2016-03-02 EP disclosed
US-20150072290-A1 COATING COMPOSITIONS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2015-03-12 US disclosed
US-8911927-B2 Compositions and processes for immersion lithography ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2014-12-16 US disclosed
US-8889344-B2 Coating compositions ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2014-11-18 US disclosed
US-8263316-B2 Electronic device manufacture ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2012-09-11 US disclosed
US-20110123937-A1 COMPOSITIONS AND PROCESSES FOR IMMERSION LITHOGRAPHY ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2011-05-26 US disclosed
US-7781141-B2 Compositions and processes for immersion lithography ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2010-08-24 US disclosed
US-7723850-B2 Electronic devices having air gaps ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2010-05-25 US disclosed
US-20050020068-A1 Plating method ROHM AND HAAS ELECTRONIC MATERIALS, L.L.C. (US) 2005-01-27 US disclosed
EP-1479793-A2 Plating method Rohm and Haas Electronic Materials, L.L.C. (US) 2004-11-24 EP disclosed
US-20040137728-A1 Air gap formation SHIPLEY COMPANY, L.L.C. (US) 2004-07-15 US disclosed
US-20040130032-A1 Electronic device manufacture SHIPLEY COMPANY, L.L.C. 2004-07-08 US disclosed
US-20040109950-A1 Dielectric materials SHIPLEY COMPANY, L.L.C. 2004-06-10 US disclosed
EP-1403925-A2 Dielectric material for electronic devices Shipley Co. L.L.C. (US) 2004-03-31 EP disclosed
US-20040052948-A1 Electronic device manufacture SHIPLEY COMPANY, L.L.C. 2004-03-18 US disclosed
EP-1398831-A2 Air gaps formation Shipley Co. L.L.C. (US) 2004-03-17 EP disclosed
US-20040033700-A1 Electronic device manufacture SHIPLEY COMPANY, L.L.C. (US) 2004-02-19 US disclosed
EP-1369908-A2 Methods for depositing pinhole-defect free organic polysilica coatings Shipley Company LLC (US) 2003-12-10 EP disclosed