Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.48 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25418952 | 0.84 | SLC18A3 (0.58) | SLC18A3EBPMEN1KMT2AKCNA5 | |
| SCHEMBL2197649 | 0.83 | SLC18A3 (0.49) | SLC18A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL29615873 | 0.83 | SLC18A3 (0.49) | SLC18A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL2936927 | 0.83 | SLC18A3 (0.49) | SLC18A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL490929 | 0.83 | SLC18A3 (0.49) | SLC18A3MEN1KMT2ASLC6A2SLC6A4 | |
| Bromide SCHEMBL19897108 | 0.82 | SLC18A3 (0.47) | SLC18A3MEN1KMT2ASLC6A2SLC6A4 | |
| Bromide SCHEMBL16799712 | 0.82 | SLC18A3 (0.47) | SLC18A3MEN1KMT2ASLC6A2SLC6A4 | |
| Bromide SCHEMBL19897327 | 0.82 | SLC18A3 (0.47) | SLC18A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL28811067 | 0.81 | SLC18A3 (0.44) | SLC18A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL25417757 | 0.81 | SLC18A3 (0.62) | SLC18A3EBPMEN1KMT2AKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713320-A2 | BCAT2 INHIBITORS | Agios Pharmaceuticals, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238820-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| EP-4430036-A2 | BCAT2 INHIBITORS | Agios Pharmaceuticals, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086539-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |