Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.49 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490929 | 1.00 | SLC18A3 (0.49) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| SCHEMBL2197649 | 1.00 | SLC18A3 (0.49) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| SCHEMBL2936927 | 1.00 | SLC18A3 (0.49) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| Bromide SCHEMBL19897108 | 0.98 | SLC18A3 (0.47) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| Bromide SCHEMBL19897327 | 0.98 | SLC18A3 (0.47) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| Bromide SCHEMBL16799712 | 0.98 | SLC18A3 (0.47) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| Bromide SCHEMBL20398790 | 0.97 | SLC18A3 (0.46) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| SCHEMBL25209581 | 0.83 | SLC18A3 (0.48) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| SCHEMBL28811067 | 0.83 | SLC18A3 (0.44) | SLC18A3OPRM1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL6431460 | 0.83 | SIGMAR1 (0.37) | SLC18A3SLC6A2SLC6A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11528906-B2 | Pyrrolidinones as herbicides | FMC CORPORATION (US) | 2022-12-20 | — | — | US | disclosed |
| US-20220281848-A1 | PYRAZOLE-SUBSTITUTED PYRROLIDINONES AS HERBICIDES | FMC CORP (US) | 2022-09-08 | — | — | US | disclosed |
| US-20220132844-A1 | PYRROLIDINONES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220132844-A1 | PYRROLIDINONES AS HERBICIDES | DDT, ARG1, PRMT1 | SLC18A3 3456/4885G6PC1 1205/4885OPRM1 1740/4885 |
| US-20220281848-A1 | PYRAZOLE-SUBSTITUTED PYRROLIDINONES AS HERBICIDES | CBR3, PRMT9, ARG1 | SLC18A3 3846/4885G6PC1 1725/4885OPRM1 1910/4885 |
| US-11528906-B2 | Pyrrolidinones as herbicides | DDT, ARG1, PRMT1 | SLC18A3 3456/4885G6PC1 1205/4885OPRM1 1740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.