Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.49 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29615873 | 1.00 | SLC18A3 (0.49) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| SCHEMBL490929 | 1.00 | SLC18A3 (0.49) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| SCHEMBL2936927 | 1.00 | SLC18A3 (0.49) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| Bromide SCHEMBL19897108 | 0.98 | SLC18A3 (0.47) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| Bromide SCHEMBL19897327 | 0.98 | SLC18A3 (0.47) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| Bromide SCHEMBL16799712 | 0.98 | SLC18A3 (0.47) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| Bromide SCHEMBL20398790 | 0.97 | SLC18A3 (0.46) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| SCHEMBL25209581 | 0.83 | SLC18A3 (0.48) | SLC18A3G6PC1OPRM1CA2SLC6A2 | |
| SCHEMBL28811067 | 0.83 | SLC18A3 (0.44) | SLC18A3OPRM1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL6431460 | 0.83 | SIGMAR1 (0.37) | SLC18A3SLC6A2SLC6A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114899-B1 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | FIRMENICH & CIE (CH) | 2010-09-22 | — | — | EP | claimed |
| US-20100098650-A1 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | FIRMENICH SA (CH) | 2010-04-22 | — | — | US | claimed |
| EP-2114899-A2 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | Firmenich S.A. (CH) | 2009-11-11 | — | — | EP | claimed |
| WO-2008093272-A2 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | FIRMENICH SA (CH) | 2008-08-07 | — | — | WO | claimed |
| CN-114773400-B | Rhodium complex, preparation method, intermediate and application thereof | 中国科学院上海有机化学研究所 | 2024-04-26 | — | — | CN | disclosed |
| CN-114773400-A | Rhodium complex, preparation method, intermediate and application thereof | 中国科学院上海有机化学研究所 | 2022-07-22 | — | — | CN | disclosed |
| CN-110944977-A | Herbicidal amides | FMC公司 | 2020-03-31 | — | — | CN | disclosed |
| US-9212335-B2 | Equilibrated dynamic mixtures to control the release of perfuming aldehydes and ketones | FIRMENICH SA (CH) | 2015-12-15 | — | — | US | disclosed |
| CN-103254121-B | A kind of method of synthesis (3R, 4R)-N-PG-4-methyl-3-methylamino piperidines | LUOYANG NORMAL UNIVERSITY (CN) | 2015-08-26 | — | — | CN | disclosed |
| CN-103254121-A | Synthesis method of (3R, 4R)-N-PG-4-methyl-3-methylaminopiperidine | UNIV LUOYANG NORMAL | 2013-08-21 | — | — | CN | disclosed |
| EP-2398769-A1 | NOVEL ORTHO-AMINOAMIDES FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2011-12-28 | — | — | EP | disclosed |
| US-7977372-B2 | Ortho aminoamides for the treatment of cancer | HOFFMANN-LA ROCHE INC. (US) | 2011-07-12 | — | — | US | disclosed |
| WO-2010094678-A1 | NOVEL ORTHO-AMINOAMIDES FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2010-08-26 | — | — | WO | disclosed |
| US-20100216806-A1 | ORTHO AMINOAMIDES FOR THE TREATMENT OF CANCER | HOFFMANN-LA ROCHE, INC. | 2010-08-26 | — | — | US | disclosed |
| US-20100098650-A1 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | FIRMENICH SA (CH) | 2010-04-22 | — | — | US | disclosed |
| EP-2114899-A2 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | Firmenich S.A. (CH) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008093272-A2 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | FIRMENICH SA (CH) | 2008-08-07 | — | — | WO | disclosed |
| EP-1904460-A1 | MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY | BRACCO IMAGING S.p.A. (IT) | 2008-04-02 | — | — | EP | disclosed |
| WO-2006136564-A9 | MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY | BRACCO IMAGING SPA (IT) | 2008-02-07 | — | — | WO | disclosed |
| WO-2006136564-A1 | MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY | BRACCO IMAGING S.P.A. (IT) | 2006-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216806-A1 | ORTHO AMINOAMIDES FOR THE TREATMENT OF CANCER | HDAC5, HDAC1, HDAC4 | SLC18A3 3272/4885G6PC1 3490/4885OPRM1 1131/4885 |
| US-20100098650-A1 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | PKM, APEH, PLG | SLC18A3 609/4885G6PC1 3965/4885OPRM1 623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.