Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 10/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2522731 | 0.93 | TSHR (0.41) | TSHRCYP3A4CYP3A5BCHESMN1; SMN2 | |
| SCHEMBL2520569 | 0.92 | TSHR (0.41) | TSHRCYP3A4CYP3A5SMN1; SMN2LMNA | |
| SCHEMBL2523610 | 0.92 | TSHR (0.41) | TSHRCYP3A4SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL2525376 | 0.89 | TSHR (0.44) | TSHRCYP3A4SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL2516243 | 0.87 | BCHE (0.37) | TSHRCYP3A4CYP3A5BCHESMN1; SMN2 | |
| SCHEMBL2519031 | 0.87 | TSHR (0.44) | TSHRCYP3A4CYP3A5SMN1; SMN2LMNA | |
| SCHEMBL2518927 | 0.86 | TSHR (0.41) | TSHRCYP3A4SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL12207242 | 0.85 | HSD11B1 (0.39) | CYP3A4CYP3A5BCHESMN1; SMN2LMNA | |
| SCHEMBL2517077 | 0.85 | CYP3A4 (0.38) | CYP3A4CYP3A5BCHESMN1; SMN2LMNA | |
| SCHEMBL2336201 | 0.85 | TSHR (0.44) | TSHRCYP3A4SMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251069-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110251069-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110251069-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| WO-2010069880-A2 | THIOPHENE, FURAN AND PYRROLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-24 | — | — | WO | disclosed |
| EP-2020851-A4 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | SYNGENTA LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| EP-2020851-A2 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | Syngenta Limited (GB) | 2009-02-11 | — | — | EP | disclosed |
| US-20070244162-A1 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2007-10-18 | — | — | US | disclosed |
| US-20070244162-A1 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2007-10-18 | — | — | US | disclosed |
| US-20070244162-A1 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2007-10-18 | — | — | US | disclosed |
| WO-2007075487-A2 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2007-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244162-A1 | SUBSTITUTED AROMATIC HETEROCYCLIC COMPOUNDS AS FUNGICIDES | NOX5, CYP3A5, API5 | TSHR 2380/4885CYP3A4 108/4885CYP3A5 2/4885 |
| US-20110251069-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | FKBP5, FKBP2, FKBP1B | TSHR 556/4885CYP3A4 1510/4885CYP3A5 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.