Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | CCR6 | P51684 | 8/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | CCR7 | P32248 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25209541 | 0.75 | LRRK2 (0.40) | HRH4CCR6PIK3C3CCR7LRRK2 | |
| Hydrochloric Acid SCHEMBL4676438 | 0.75 | ROCK1 (0.44) | HRH4PIK3C3KDM4EGAA | |
| SCHEMBL19413524 | 0.75 | COMT (0.39) | HRH4PIK3C3LRRK2 | |
| SCHEMBL23497385 | 0.71 | KDM4E (0.47) | HRH4CCR6CCR7LRRK2GCK | |
| SCHEMBL29971106 | 0.71 | KDM4E (0.47) | HRH4CCR6CCR7LRRK2GCK | |
| SCHEMBL17645852 | 0.69 | LMNA (0.62) | PIK3C3KDM4EGAA | |
| SCHEMBL29086274 | 0.68 | LNPEP (0.40) | HRH4CCR6CCR7LRRK2GCK | |
| SCHEMBL29086273 | 0.67 | KCNH2 (0.35) | HRH4CCR6CCR7LRRK2GCK | |
| SCHEMBL23845592 | 0.64 | KDM4E (0.51) | CCR6KDM4EGAA | |
| SCHEMBL13874660 | 0.63 | LMNA (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |