Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 3/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | TET3 | O43151 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 1/20 | 0.47 |
| ▸ | ASPH | Q12797 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.47 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.47 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.47 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23497385 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1ALKBH5FTOKDM6B | |
| SCHEMBL7930744 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1ALKBH5FTOKDM6B | |
| SCHEMBL29086274 | 0.77 | LNPEP (0.40) | EGLN2EGLN1GCKAKR1C3CCR6 | |
| SCHEMBL20790368 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1ALKBH5FTOKDM6B | |
| SCHEMBL30525023 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1ALKBH5FTOKDM6B | |
| SCHEMBL28654286 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1ALKBH5FTOKDM6B | |
| SCHEMBL19413524 | 0.75 | COMT (0.39) | ALDH1A1LRRK2HRH4 | |
| SCHEMBL25209541 | 0.75 | LRRK2 (0.40) | CCR6CCR7LRRK2HRH4 | |
| SCHEMBL24369107 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1ALKBH5FTOKDM6B | |
| SCHEMBL29488865 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1ALKBH5FTOKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279747-B | FYN and VEGFR2 kinase inhibitors | 罗达制药生物技术有限责任公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115279747-A | Novel fYN and VEGFR2 kinase inhibitors | 罗达制药生物技术有限责任公司 | 2022-11-01 | — | — | CN | disclosed |