Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.30 |
| ▸ | CDC25B | P30305 | 2/20 | 0.30 |
| ▸ | CCNK | O75909 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15084421 | 0.90 | TMPRSS2 (0.39) | TMPRSS2HTR1ABCHEACHEPTPN1 | |
| SCHEMBL25273419 | 0.86 | TMPRSS2 (0.36) | TMPRSS2HTR1ABCHEPTPN1CDC25B | |
| SCHEMBL29727834 | 0.85 | PDE2A (0.35) | TMPRSS2HTR1ABCHEACHEPTPN1 | |
| SCHEMBL20477154 | 0.85 | PDE2A (0.35) | TMPRSS2HTR1ABCHEACHEPTPN1 | |
| SCHEMBL27086511 | 0.85 | PDE2A (0.35) | TMPRSS2HTR1ABCHEACHEPTPN1 | |
| SCHEMBL12243178 | 0.85 | PDE2A (0.35) | TMPRSS2HTR1ABCHEACHEPTPN1 | |
| SCHEMBL17712276 | 0.85 | PDE2A (0.35) | TMPRSS2HTR1ABCHEACHEPTPN1 | |
| SCHEMBL25259971 | 0.85 | BCHE (0.36) | TMPRSS2HTR1ABCHEACHEPTPN1 | |
| SCHEMBL20553048 | 0.85 | PDE2A (0.35) | TMPRSS2HTR1ABCHEACHEPTPN1 | |
| SCHEMBL28408184 | 0.85 | HTR1A (0.33) | TMPRSS2HTR1ABCHEACHEPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102472-A1 | ANTIVIRAL PRODRUGS AND FORMULATIONS THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-06-08 | — | — | WO | disclosed |