Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23735099 | 0.88 | HDAC8 (0.56) | HDAC8TAS1R3TAS1R1TAS1R2TRPM8 | |
| SCHEMBL20812217 | 0.84 | HDAC8 (0.53) | HDAC8TAS1R3TAS1R1TAS1R2TRPM8 | |
| SCHEMBL1557170 | 0.84 | HDAC8 (0.53) | HDAC8TAS1R3TAS1R1TAS1R2TRPM8 | |
| SCHEMBL8276072 | 0.82 | HDAC8 (0.61) | HDAC8TAS1R3TAS1R1TAS1R2TRPM8 | |
| SCHEMBL29742938 | 0.79 | MAOB (0.55) | HDAC8TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL29448761 | 0.79 | PARP1 (0.61) | TAS1R3TAS1R1TAS1R2TRPM8KAT6A | |
| SCHEMBL711132 | 0.79 | PARP1 (0.61) | TAS1R3TAS1R1TAS1R2TRPM8KAT6A | |
| SCHEMBL697586 | 0.79 | MAOB (0.55) | HDAC8TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL690501 | 0.79 | KAT6A (0.54) | HDAC8TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL7055657 | 0.78 | MRGPRX4 (0.63) | HDAC8TAS1R3TAS1R1TAS1R2KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |