Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.42 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23735099 | 0.86 | HDAC8 (0.56) | HDAC8TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL25213964 | 0.84 | HDAC8 (0.57) | HDAC8TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL2353790 | 0.83 | CES2 (0.59) | NPC1RAB9A | |
| SCHEMBL1557170 | 0.82 | HDAC8 (0.53) | HDAC8TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL8276072 | 0.81 | HDAC8 (0.61) | HDAC8TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL20812516 | 0.81 | AKR1C3 (0.58) | HDAC8NPC1RAB9A | |
| SCHEMBL22952541 | 0.78 | KAT6A (0.52) | HDAC8TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL29742938 | 0.78 | MAOB (0.55) | HDAC8TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL697586 | 0.78 | MAOB (0.55) | HDAC8TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL690501 | 0.77 | KAT6A (0.54) | HDAC8TAS1R3TAS1R1TAS1R2KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190076539-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 Theraprutics, Inc. (US) | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190076539-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | GCGR, STUB1, GID4 | HDAC8 3426/4885TAS1R3 3541/4885TAS1R1 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.