Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.36 |
| ▸ | FAAH | O00519 | 7/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30473979 | 0.95 | FAAH (0.36) | GRIN2BHDAC1HDAC6FAAHNTRK1 | |
| SCHEMBL25214377 | 0.89 | HDAC1 (0.47) | HDAC1HDAC6FAAHCA12CA1 | |
| SCHEMBL25675531 | 0.89 | HDAC1 (0.47) | HDAC1HDAC6FAAHCA12CA1 | |
| SCHEMBL25212314 | 0.88 | CA12 (0.36) | HDAC1HDAC6CA12CA1CA2 | |
| SCHEMBL24073262 | 0.87 | HDAC1 (0.48) | GRIN2BHDAC1HDAC6 | |
| SCHEMBL31017693 | 0.87 | HDAC1 (0.48) | GRIN2BHDAC1HDAC6 | |
| SCHEMBL25208583 | 0.87 | FAAH (0.43) | HDAC1HDAC6FAAHCA12CA1 | |
| SCHEMBL25212827 | 0.86 | DGAT2 (0.39) | HDAC1HDAC6 | |
| Trifluoroacetic Acid SCHEMBL30474005 | 0.84 | HDAC1 (0.43) | HDAC1HDAC6FAAHHDAC3HDAC2 | |
| Trifluoroacetic Acid SCHEMBL30371030 | 0.84 | HDAC1 (0.46) | GRIN2BHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099561-A1 | SUBSTITUTED N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2023-06-08 | — | — | WO | disclosed |