Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25214377 | 1.00 | HDAC1 (0.47) | HDAC1HDAC6NPC1RAB9ANUDT1 | |
| Trifluoroacetic Acid SCHEMBL30474005 | 0.95 | HDAC1 (0.43) | HDAC1HDAC6NPC1RAB9ANUDT1 | |
| SCHEMBL25212314 | 0.89 | CA12 (0.36) | HDAC1HDAC6NTRK1CA12CA1 | |
| SCHEMBL25215141 | 0.89 | GRIN2B (0.37) | HDAC1HDAC6NTRK1CA12CA1 | |
| SCHEMBL24073262 | 0.88 | HDAC1 (0.48) | HDAC1HDAC6 | |
| SCHEMBL31017693 | 0.88 | HDAC1 (0.48) | HDAC1HDAC6 | |
| SCHEMBL25208583 | 0.88 | FAAH (0.43) | HDAC1HDAC6CA12CA1CA2 | |
| SCHEMBL25212827 | 0.86 | DGAT2 (0.39) | HDAC1HDAC6PDE4BPDE4D | |
| Trifluoroacetic Acid SCHEMBL30371030 | 0.86 | HDAC1 (0.46) | HDAC1HDAC6 | |
| Trifluoroacetic Acid SCHEMBL30474039 | 0.84 | HDAC1 (0.35) | HDAC1HDAC6NTRK1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099561-A1 | SUBSTITUTED N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2023-06-08 | — | — | WO | disclosed |