Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | DPP4 | P27487 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.62 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.62 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.62 |
| ▸ | GAPDH | P04406 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | STAT6 | P42226 | 1/20 | 0.62 |
| ▸ | PI4KA | P42356 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.62 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.62 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.62 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.62 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12212814 | 1.00 | ADORA1 (0.65) | ADORA1ADORA3ADORA2AADORA2BKMT2A | |
| SCHEMBL2521597 | 1.00 | ADORA1 (0.65) | ADORA1ADORA3ADORA2AADORA2BKMT2A | |
| SCHEMBL18034317 | 1.00 | ADORA1 (0.65) | ADORA1ADORA3ADORA2AADORA2BKMT2A | |
| SCHEMBL2524242 | 0.90 | ADORA1 (0.66) | ADORA1ADORA3ADORA2AADORA2BKMT2A | |
| SCHEMBL2524241 | 0.90 | ADORA1 (0.66) | ADORA1ADORA3ADORA2AADORA2BKMT2A | |
| SCHEMBL18034349 | 0.88 | ADORA3 (0.53) | ADORA1ADORA3SMN1; SMN2TSHR | |
| SCHEMBL13785240 | 0.88 | ADORA3 (0.53) | ADORA1ADORA3SMN1; SMN2TSHR | |
| SCHEMBL2518239 | 0.87 | ADORA1 (0.65) | ADORA1ADORA3ADORA2AADORA2BKMT2A | |
| SCHEMBL2518244 | 0.87 | ADORA1 (0.65) | ADORA1ADORA3ADORA2AADORA2BKMT2A | |
| SCHEMBL12212836 | 0.87 | RNASEL (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2006293-B1 | 2'-HYDROXYL-MODIFIED RIBONUCLEOSIDE DERIVATIVE | TOKYO INST TECH (JP) | 2016-08-24 | — | — | EP | disclosed |
| US-8039611-B2 | 2′-hydroxyl group-modified ribonucleoside derivatives | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20100016574-A1 | 2'-Hydroxyl Group-Modified Ribonucleoside Derivatives | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2006293-A9 | 2'-HYDROXYL-MODIFIED RIBONUCLEOSIDE DERIVATIVE | Tokyo Institute of Technology (JP) | 2009-07-22 | — | — | EP | disclosed |
| EP-2006293-A9 | 2'-HYDROXYL-MODIFIED RIBONUCLEOSIDE DERIVATIVE | Tokyo Institute of Technology (JP) | 2009-07-22 | — | — | EP | disclosed |
| EP-2006293-A2 | 2'-HYDROXYL-MODIFIED RIBONUCLEOSIDE DERIVATIVE | Tokyo Institute of Technology (JP) | 2008-12-24 | — | — | EP | disclosed |
| EP-2006293-A2 | 2'-HYDROXYL-MODIFIED RIBONUCLEOSIDE DERIVATIVE | Tokyo Institute of Technology (JP) | 2008-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016574-A1 | 2'-Hydroxyl Group-Modified Ribonucleoside Derivatives | RNASEH1, RNASEL, NSUN2 | ADORA1 2037/4885ADORA3 1729/4885ADORA2A 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.