Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929918 | 0.86 | KDM4E (0.55) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL2523027 | 0.84 | KDM4E (0.53) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL2231079 | 0.84 | KDM4E (0.57) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL2353928 | 0.80 | KDM4E (0.58) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL11729407 | 0.80 | KDM4E (0.49) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL2228797 | 0.79 | KDM4E (0.61) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL11739119 | 0.77 | KMT2A (0.47) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL27819764 | 0.77 | EP300 (0.55) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL2229397 | 0.76 | KDM4E (0.55) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL2229187 | 0.76 | ALDH1A1 (0.55) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062787-A1 | BIOLUMINESCENCE IMAGING OF MYELOPEROXIDASE ACTIVITY IN VIVO, METHODS, COMPOSITIONS AND APPARATUSES THEREFOR | WASHINGTON UNIVERSITY (US) | 2010-06-03 | — | — | WO | claimed |
| US-6077461-A | Cationic chemiluminescent monomers and polymers | NALCO CHEMICAL COMPANY (US) | 2000-06-20 | — | — | US | claimed |
| US-8652442-B2 | Bioluminescence imaging of myeloperoxidase activity in vivo, methods, compositions and apparatuses therefor | WASHINGTON UNIVERSITY (US) | 2014-02-18 | — | — | US | disclosed |
| US-8652442-B2 | Bioluminescence imaging of myeloperoxidase activity in vivo, methods, compositions and apparatuses therefor | WASHINGTON UNIVERSITY (US) | 2014-02-18 | — | — | US | disclosed |
| US-8652442-B2 | Bioluminescence imaging of myeloperoxidase activity in vivo, methods, compositions and apparatuses therefor | WASHINGTON UNIVERSITY (US) | 2014-02-18 | — | — | US | disclosed |
| US-20110250145-A1 | BIOLUMINESCENCE IMAGING OF MYELOPEROXIDASE ACTIVITY IN VIVO, METHODS, COMPOSITIONS AND APPARATUSES THEREFOR | WASHINGTON UNIVERSITY (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110250145-A1 | BIOLUMINESCENCE IMAGING OF MYELOPEROXIDASE ACTIVITY IN VIVO, METHODS, COMPOSITIONS AND APPARATUSES THEREFOR | WASHINGTON UNIVERSITY (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110250145-A1 | BIOLUMINESCENCE IMAGING OF MYELOPEROXIDASE ACTIVITY IN VIVO, METHODS, COMPOSITIONS AND APPARATUSES THEREFOR | WASHINGTON UNIVERSITY (US) | 2011-10-13 | — | — | US | disclosed |
| WO-2010062787-A1 | BIOLUMINESCENCE IMAGING OF MYELOPEROXIDASE ACTIVITY IN VIVO, METHODS, COMPOSITIONS AND APPARATUSES THEREFOR | WASHINGTON UNIVERSITY (US) | 2010-06-03 | — | — | WO | disclosed |
| US-6077461-A | Cationic chemiluminescent monomers and polymers | NALCO CHEMICAL COMPANY (US) | 2000-06-20 | — | — | US | disclosed |
| WO-2000018850-A1 | CATIONIC CHEMILUMINESCENT MONOMERS AND POLYMERS | NALCO CHEMICAL COMPANY (US) | 2000-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110250145-A1 | BIOLUMINESCENCE IMAGING OF MYELOPEROXIDASE ACTIVITY IN VIVO, METHODS, COMPOSITIONS AND APPARATUSES THEREFOR | MPO, GPX1, MMP8 | SMN1; SMN2 3646/4885KDM4E 4697/4885MEN1 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.