SCHEMBL25216720

SCHEMBL25216720

CCC(=O)Cc1ccc2occc2c1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 5/20 0.49
CTNNB1 P35222 7/20 0.46
WNT3A P56704 7/20 0.46
CYP2A6 P11509 1/20 0.41
EPM2A O95278 1/20 0.41
PTPRC P08575 1/20 0.41
PTPN6 P29350 1/20 0.41
CDC14A Q9UNH5 1/20 0.41
PTPN22 Q9Y2R2 1/20 0.41
CA2 P00918 2/20 0.40
MRGPRX4 Q96LA9 1/20 0.39
CA12 O43570 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
GAA P10253 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30427150 1.00 HTR1B (0.49) HTR1BCTNNB1WNT3ACYP2A6EPM2A
SCHEMBL6024493 0.88 CTNNB1 (0.47) HTR1BCTNNB1WNT3ACYP2A6EPM2A
SCHEMBL24111926 0.87 HTR1B (0.49) HTR1BCTNNB1WNT3ACYP2A6MRGPRX4
SCHEMBL1922396 0.83 HTR1B (0.50) HTR1BCTNNB1WNT3ACYP2A6EPM2A
SCHEMBL30426911 0.83 HTR1B (0.50) HTR1BCTNNB1WNT3ACYP2A6EPM2A
SCHEMBL103859 0.81 GAA (0.53) HTR1BCTNNB1WNT3ACYP2A6EPM2A
SCHEMBL7429901 0.80 PKM (0.47) HTR1BCTNNB1WNT3ACYP2A6CA2
SCHEMBL5809234 0.80 CTNNB1 (0.48) HTR1BCTNNB1WNT3ACYP2A6EPM2A
SCHEMBL27589293 0.80 HTR1B (0.53) HTR1BCTNNB1WNT3ACYP2A6EPM2A
SCHEMBL7442715 0.79 HTR1B (0.50) HTR1BCTNNB1WNT3AMRGPRX4TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250019357-A1 BENZOFURAN SALT MORPHIC FORMS AND MIXTURES FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2025-01-16 US disclosed
EP-4444296-A2 BENZOFURAN SALT MORPHIC FORMS AND MIXTURES FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT Tactogen Inc. (US) 2024-10-16 EP disclosed
US-11767305-B2 Advantageous benzofuran compositions for mental disorders or enhancement TACTOGEN INC (US) 2023-09-26 US disclosed
US-11767305-B2 Advantageous benzofuran compositions for mental disorders or enhancement TACTOGEN INC (US) 2023-09-26 US disclosed
WO-2023107653-A2 BENZOFURAN SALT MORPHIC FORMS AND MIXTURES FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-06-15 WO disclosed
WO-2023107715-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-06-15 WO disclosed
US-20230150963-A1 ADVANTAGEOUS BENZOFURAN COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT TACTOGEN INC. (US) 2023-05-18 US disclosed
US-20230150963-A1 ADVANTAGEOUS BENZOFURAN COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT TACTOGEN INC. (US) 2023-05-18 US disclosed
CN-116075300-A Advantageous benzofuran compositions for mental disorders or mental enhancement 泰科根公司 2023-05-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767305-B2 Advantageous benzofuran compositions for mental disorders or enhancement BDNF, CREBBP, ELF3 HTR1B 273/4885CTNNB1 2504/4885WNT3A 3773/4885
US-20230150963-A1 ADVANTAGEOUS BENZOFURAN COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT BDNF, CREBBP, ELF3 HTR1B 273/4885CTNNB1 2504/4885WNT3A 3773/4885
US-20250019357-A1 BENZOFURAN SALT MORPHIC FORMS AND MIXTURES FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT ELF3, BDNF, ETV6 HTR1B 373/4885CTNNB1 2746/4885WNT3A 3033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.