Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | PRSS12 | P56730 | 6/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.50 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30446542 | 1.00 | KMT2A (0.55) | KMT2AMEN1PRSS12MMP2MMP9 | |
| SCHEMBL25247637 | 0.90 | PRSS12 (0.63) | KMT2AMEN1PRSS12MMP2MMP9 | |
| SCHEMBL30445806 | 0.90 | PRSS12 (0.63) | KMT2AMEN1PRSS12MMP2MMP9 | |
| SCHEMBL25206721 | 0.90 | MMP2 (0.68) | KMT2AMEN1PRSS12MMP2MMP9 | |
| SCHEMBL30442876 | 0.90 | MMP2 (0.68) | KMT2AMEN1PRSS12MMP2MMP9 | |
| SCHEMBL25232314 | 0.83 | MAPT (0.59) | KMT2AMEN1PRSS12MMP2MMP9 | |
| SCHEMBL30445817 | 0.83 | MAPT (0.59) | KMT2AMEN1PRSS12MMP2MMP9 | |
| SCHEMBL30445839 | 0.81 | MMP2 (0.66) | KMT2AMEN1MMP2MMP9MMP8 | |
| SCHEMBL25202397 | 0.81 | MMP2 (0.66) | KMT2AMEN1MMP2MMP9MMP8 | |
| SCHEMBL14381560 | 0.81 | PRSS12 (0.72) | KMT2AMEN1PRSS12MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4153172-B1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NAT RECH SCIENT (FR) | 2024-11-27 | — | — | EP | disclosed |
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-08 | — | — | US | disclosed |
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-08 | — | — | US | disclosed |
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | TARBP1, NFATC1, TARDBP | KMT2A 1423/4885MEN1 4850/4885PRSS12 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.