Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.66 |
| ▸ | MMP13 | P45452 | 5/20 | 0.66 |
| ▸ | MMP9 | P14780 | 4/20 | 0.66 |
| ▸ | MMP8 | P22894 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | COMT | P21964 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25202397 | 1.00 | MMP2 (0.66) | MMP2MMP13MMP9MMP8MAPT | |
| SCHEMBL25206721 | 0.91 | MMP2 (0.68) | MMP2MMP13MMP9MMP8MAPT | |
| SCHEMBL30442876 | 0.91 | MMP2 (0.68) | MMP2MMP13MMP9MMP8MAPT | |
| SCHEMBL30445806 | 0.84 | PRSS12 (0.63) | MMP2MMP13MMP9MMP8MAPT | |
| SCHEMBL25247637 | 0.84 | PRSS12 (0.63) | MMP2MMP13MMP9MMP8MAPT | |
| SCHEMBL25232314 | 0.82 | MAPT (0.59) | MMP2MMP13MMP9MMP8MAPT | |
| SCHEMBL6528511 | 0.82 | HPSE (0.67) | MMP2MMP13MMP9MMP8MAPT | |
| SCHEMBL30445817 | 0.82 | MAPT (0.59) | MMP2MMP13MMP9MMP8MAPT | |
| SCHEMBL6264436 | 0.82 | MMP2 (0.69) | MMP2MMP13MMP9MMP8MAPT | |
| SCHEMBL25217151 | 0.81 | KMT2A (0.55) | MMP2MMP13MMP9MMP8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | TARBP1, NFATC1, TARDBP | MMP2 4195/4885MMP13 3848/4885MMP9 4127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.