Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | LMNA | P02545 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25279687 | 1.00 | MAPT (0.72) | MAPTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL25201205 | 1.00 | MAPT (0.72) | MAPTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL18099457 | 0.93 | MAPT (0.74) | MAPTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL25217693 | 0.92 | RECQL (0.74) | MAPTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL25217936 | 0.90 | MEN1 (0.71) | MAPTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL30382606 | 0.90 | MEN1 (0.71) | MAPTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL25185060 | 0.87 | MAPT (0.66) | MAPTL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL30383618 | 0.85 | MEN1 (0.71) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL25199616 | 0.85 | MEN1 (0.71) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL25194782 | 0.85 | MEN1 (0.67) | MAPTL3MBTL1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |