Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | BID | P55957 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786272 | 1.00 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL25200311 | 1.00 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL29498156 | 1.00 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL5820539 | 0.98 | PNMT (0.58) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7939929 | 0.94 | PNMT (0.60) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL6676505 | 0.92 | PNMT (0.66) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL6674622 | 0.92 | PNMT (0.66) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL6675794 | 0.90 | PNMT (0.68) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL5355390 | 0.87 | PNMT (0.64) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL6674911 | 0.87 | PNMT (0.68) | PNMTDRD2DRD4DRD3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159457-A1 | FLUORENE DERIVATIVES, POLYMERS OBTAINED FROM SAID FLUORENE DERIVATIVES AND METHOD FOR PREPARING THE SAME | IRPC PUBLIC COMPANY LIMITED (TH) | 2023-05-25 | — | — | US | disclosed |
| CN-112740018-A | Narrow absorbing polymeric nanoparticles and related methods | 华盛顿大学 | 2021-04-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159457-A1 | FLUORENE DERIVATIVES, POLYMERS OBTAINED FROM SAID FLUORENE DERIVATIVES AND METHOD FOR PREPARING THE SAME | TERT, F12, F3 | PNMT 532/4885DRD2 142/4885DRD4 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.