Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25217852 | 0.98 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL29498156 | 0.98 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL2786272 | 0.98 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL25200311 | 0.98 | PNMT (0.57) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7939929 | 0.95 | PNMT (0.60) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL6675794 | 0.92 | PNMT (0.68) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL6676505 | 0.90 | PNMT (0.66) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL6674622 | 0.90 | PNMT (0.66) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL5355390 | 0.88 | PNMT (0.64) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL6674911 | 0.88 | PNMT (0.68) | PNMTDRD2DRD4DRD3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101230399-B | Method for detecting DNA methylation | CHINESE ACAD INST CHEMISTRY | 2010-06-02 | — | — | CN | disclosed |
| CN-101230399-A | Method for detecting DNA methylation | CHINESE ACAD INST CHEMISTRY (CN) | 2008-07-30 | — | — | CN | disclosed |
| WO-2006137818-A1 | CATALYST COMPONENTS AND THEIR USE IN THE POLYMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20050148460-A1 | Catalyst components and their use in the polymerization of olefins | FINA TECHNOLOGY, INC. | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148460-A1 | Catalyst components and their use in the polymerization of olefins | NPY5R, SSTR5, FGR | PNMT 534/4885DRD2 830/4885DRD4 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.