SCHEMBL25217879

SCHEMBL25217879

COc1cc(O)ccc1C(=O)/C=C/c1ccccc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.84
CAPN1 P07384 2/20 0.84
PARP1 P09874 1/20 0.84
MAOA P21397 1/20 0.84
CTSL P07711 2/20 0.76
MAPT P10636 7/20 0.75
KMT2A Q03164 6/20 0.75
MEN1 O00255 5/20 0.75
NPC1 O15118 2/20 0.75
RAB9A P51151 2/20 0.75
XDH P47989 1/20 0.69
ABCG2 Q9UNQ0 5/20 0.67
CYP3A4 P08684 3/20 0.67
TDP1 Q9NUW8 3/20 0.67
ALDH1A1 P00352 2/20 0.67
HPGD P15428 2/20 0.67
ALOX15 P16050 2/20 0.67
MAPK1 P28482 2/20 0.67
SMN1; SMN2 Q16637 2/20 0.67
HSD17B10 Q99714 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25214503 1.00 MAOB (0.84) MAOBCAPN1PARP1MAOACTSL
SCHEMBL2027068 0.91 MAOB (1.00) MAOBCAPN1PARP1MAOACTSL
SCHEMBL799750 0.91 MAOB (1.00) MAOBCAPN1PARP1MAOACTSL
SCHEMBL29634551 0.91 MAOB (1.00) MAOBCAPN1PARP1MAOACTSL
SCHEMBL30383807 0.91 MAOB (1.00) MAOBCAPN1PARP1MAOACTSL
SCHEMBL24283301 0.87 MAOB (0.86) MAOBCAPN1PARP1MAOACTSL
SCHEMBL25195523 0.87 MAOB (0.86) MAOBCAPN1PARP1MAOACTSL
SCHEMBL25202393 0.86 CTSL (1.00) MAOBCAPN1PARP1MAOACTSL
SCHEMBL4030789 0.86 MAPT (1.00) MAPTKMT2AMEN1NPC1RAB9A
SCHEMBL4030793 0.86 MAPT (1.00) MAPTKMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885CAPN1 2288/4885PARP1 3850/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885CAPN1 1989/4885PARP1 3366/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885CAPN1 1989/4885PARP1 3366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.