Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 1.00 |
| ▸ | CAPN1 | P07384 | 1/20 | 1.00 |
| ▸ | PARP1 | P09874 | 1/20 | 1.00 |
| ▸ | MAOA | P21397 | 1/20 | 1.00 |
| ▸ | CTSL | P07711 | 2/20 | 0.84 |
| ▸ | XDH | P47989 | 1/20 | 0.82 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634551 | 1.00 | MAOB (1.00) | MAOBCAPN1PARP1MAOACTSL | |
| SCHEMBL30383807 | 1.00 | MAOB (1.00) | MAOBCAPN1PARP1MAOACTSL | |
| SCHEMBL2027068 | 1.00 | MAOB (1.00) | MAOBCAPN1PARP1MAOACTSL | |
| SCHEMBL24283301 | 0.93 | MAOB (0.86) | MAOBCAPN1PARP1MAOACTSL | |
| SCHEMBL25195523 | 0.93 | MAOB (0.86) | MAOBCAPN1PARP1MAOACTSL | |
| SCHEMBL25202393 | 0.92 | CTSL (1.00) | MAOBCAPN1PARP1MAOACTSL | |
| SCHEMBL25217879 | 0.91 | MAOB (0.84) | MAOBCAPN1PARP1MAOACTSL | |
| SCHEMBL25214503 | 0.91 | MAOB (0.84) | MAOBCAPN1PARP1MAOACTSL | |
| SCHEMBL21527708 | 0.90 | XDH (1.00) | MAOBCAPN1PARP1MAOACTSL | |
| SCHEMBL21527710 | 0.90 | XDH (1.00) | MAOBCAPN1PARP1MAOACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230029027-A1 | COMPOSITIONS AND METHODS FOR USING GENETICALLY MODIFIED ENZYMES | RENEW BIOPHARMA, INC. | 2023-01-26 | — | — | US | claimed |
| WO-2020210810-A9 | COMPOSITIONS AND METHODS FOR USING GENETICALLY MODIFIED ENZYMES | RENEW BIOPHARMA, INC. (US) | 2020-11-26 | — | — | WO | claimed |
| WO-2020210810-A1 | COMPOSITIONS AND METHODS FOR USING GENETICALLY MODIFIED ENZYMES | RENEW BIOPHARMA, INC. (US) | 2020-10-15 | — | — | WO | claimed |
| WO-2019183152-A1 | COMPOSITIONS AND METHODS FOR USING GENETICALLY MODIFIED ENZYMES | RENEW BIOPHARMA, INC. (US) | 2019-09-26 | — | — | WO | claimed |
| US-12540315-B2 | Compositions and methods for using genetically modified enzymes | RENEW BIOPHARMA, INC. (US) | 2026-02-03 | — | — | US | disclosed |
| EP-4499222-A2 | COMPOSITIONS AND METHODS FOR PROMOTING HAIR GROWTH | Locus Solutions IPCO, LLC (US) | 2025-02-05 | — | — | EP | disclosed |
| US-20240366488-A1 | COMPOSITIONS AND METHODS FOR PROMOTING HAIR GROWTH | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2024-11-07 | — | — | US | disclosed |
| EP-4403042-A2 | FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | Mars, Incorporated (US) | 2024-07-24 | — | — | EP | disclosed |
| EP-3229612-B1 | USE OF FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS INC (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023192979-A2 | COMPOSITIONS AND METHODS FOR PROMOTING HAIR GROWTH | LOCUS SOLUTIONS IPCO, LLC (US) | 2023-10-05 | — | — | WO | disclosed |
| US-20230029027-A1 | COMPOSITIONS AND METHODS FOR USING GENETICALLY MODIFIED ENZYMES | RENEW BIOPHARMA, INC. | 2023-01-26 | — | — | US | disclosed |
| US-20210301267-A1 | COMPOSITIONS AND METHODS FOR USING GENETICALLY MODIFIED ENZYMES | RENEW BIOPHARMA, INC. | 2021-09-30 | — | — | US | disclosed |
| US-20110306073-A1 | METHOD AND COMPOSITIONS FOR DETERMINING ENZYMATIC ACTIVITY AND SPECIFICITY OF METHYLTRANSFERASES | THE SAMUEL ROBERTS NOBLE FOUNDATION | 2011-12-15 | — | — | US | disclosed |
| US-7966133-B2 | Method of identifying a potential substrates of an O-methyltransferase | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090192720-A1 | METHODS AND COMPOSITIONS FOR DETERMINING ENZYMATIC ACTIVITY AND SPECIFICITY OF METHYLTRANSFERASES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2009-07-30 | — | — | US | disclosed |
| US-7384759-B2 | Methods and compositions for determinig enzymatic activity and specificity of chalcone O-methyltransferases | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2008-06-10 | — | — | US | disclosed |
| US-7384759-B2 | Methods and compositions for determinig enzymatic activity and specificity of chalcone O-methyltransferases | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2008-06-10 | — | — | US | disclosed |
| US-20040111218-A1 | Methods and compositions for determining enzymatic activity and specificity of methlytransferases | SAMUEL ROBERTS NOBLE FOUNDATION, THE | 2004-06-10 | — | — | US | disclosed |
| WO-2003006987-A9 | METHODS AND COMPOSITIONS FOR DETERMINING ENZYMATIC ACTIVITY AND SPECIFICITY OF METHYLTRANSFERASES | SALK INST FOR BIOLOGICAL STUDI (US) | 2003-04-24 | — | — | WO | disclosed |
| WO-2003006987-A1 | METHODS AND COMPOSITIONS FOR DETERMINING ENZYMATIC ACTIVITY AND SPECIFICITY OF METHYLTRANSFERASES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2003-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540315-B2 | Compositions and methods for using genetically modified enzymes | COASY, CYP4F3, CYP4F11 | MAOB 281/4885CAPN1 3997/4885PARP1 3426/4885 |
| US-20240366488-A1 | COMPOSITIONS AND METHODS FOR PROMOTING HAIR GROWTH | NGF, FGF1, NTRK2 | MAOB 253/4885CAPN1 2202/4885PARP1 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.