Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25252214 | 0.84 | CYP3A4 (0.42) | MAOAALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL29450087 | 0.81 | L3MBTL1 (0.46) | MAOAALDH1A1MAPTKDM4EPKM | |
| SCHEMBL25421184 | 0.74 | KCNJ1 (0.52) | MAOAALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL854481 | 0.73 | CYP3A4 (0.53) | MAOAALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL2729075 | 0.72 | CYP3A4 (0.41) | MAOAALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL3559618 | 0.71 | CHRM4 (0.42) | KDM4EMEN1KMT2A | |
| SCHEMBL25212302 | 0.69 | L3MBTL1 (0.46) | ALDH1A1MAPTKDM4ELMNAGAA | |
| SCHEMBL16520532 | 0.69 | CYP3A4 (0.49) | MAOAALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL16505233 | 0.69 | CYP3A4 (0.50) | MAOAMAPTKDM4EGAACYP3A4 | |
| SCHEMBL25219763 | 0.68 | KCNJ1 (0.56) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188373-A1 | LOW MOLECULAR WEIGHT PROTEIN DEGRADERS AND THEIR APPLICATIONS | Captor Therapeutics S.A. (PL) | 2023-06-07 | — | — | EP | disclosed |