Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY4 | P51582 | 5/20 | 0.80 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.80 |
| ▸ | CHAT | P28329 | 4/20 | 0.77 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.77 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.77 |
| ▸ | HPGDS | O60760 | 1/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | APEX1 | P27695 | 1/20 | 0.74 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.72 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.72 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.70 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.70 |
| ▸ | GNG2 | P59768 | 4/20 | 0.70 |
| ▸ | GNB1 | P62873 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30392069 | 1.00 | P2RY4 (0.80) | P2RY4P2RY2CHATENPP3ENPP1 | |
| SCHEMBL13214132 | 0.94 | CHAT (0.79) | P2RY4P2RY2CHATENPP3ENPP1 | |
| SCHEMBL14641913 | 0.92 | CHAT (0.85) | P2RY4P2RY2CHATENPP3ENPP1 | |
| SCHEMBL8757384 | 0.90 | CHAT (0.67) | P2RY4P2RY2CHATENPP3ENPP1 | |
| SCHEMBL430581 | 0.90 | HPGDS (0.81) | P2RY4P2RY2CHATENPP3ENPP1 | |
| SCHEMBL14451098 | 0.90 | HPGDS (0.84) | P2RY4P2RY2CHATENPP3ENPP1 | |
| SCHEMBL13213990 | 0.90 | HPGDS (0.91) | P2RY4P2RY2CHATENPP3ENPP1 | |
| SCHEMBL29517169 | 0.90 | HPGDS (0.81) | P2RY4P2RY2CHATENPP3ENPP1 | |
| SCHEMBL13214128 | 0.89 | P2RY12 (0.83) | P2RY4P2RY2CHATENPP3ENPP1 | |
| SCHEMBL31722288 | 0.89 | P2RY4 (1.00) | P2RY4P2RY2USP2APEX1P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426280-B1 | PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS | GURBA ALEXANDRE (CH) | 2026-03-18 | — | — | EP | disclosed |
| US-20250057791-A1 | PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS | GURBA ALEXANDRE (CH) | 2025-02-20 | — | — | US | disclosed |
| WO-2023111938-A1 | PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS | GURBA, Alexandre (CH) | 2023-06-22 | — | — | WO | disclosed |
| EP-4197533-A1 | PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS | Guerin, Patrick (CH) | 2023-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250057791-A1 | PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS | P2RX2, P2RX3, P2RX1 | P2RY4 12/4885P2RY2 7/4885CHAT 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.