SCHEMBL25220587

SCHEMBL25220587

COC(=O)C1C(C)=CC(OC(C)=O)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TSHR P16473 3/20 0.35
CYP3A4 P08684 2/20 0.34
USP2 O75604 1/20 0.34
ALDH1A1 P00352 4/20 0.34
HTT P42858 1/20 0.32
CYP19A1 P11511 1/20 0.32
PTGS1 P23219 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 2/20 0.31
CYP2C9 P11712 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.31
ABCB11 O95342 1/20 0.31
ESR1 P03372 1/20 0.31
PGR P06401 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
AR P10275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25232601 0.88 CYP3A4 (0.36) TSHRCYP3A4USP2ALDH1A1CYP19A1
SCHEMBL31348323 0.88 CYP3A4 (0.36) TSHRCYP3A4USP2ALDH1A1CYP19A1
SCHEMBL29275519 0.86 SMN1; SMN2 (0.32) GAAMAPTNPSR1TSHRCYP3A4
SCHEMBL25206845 0.85 LMNA (0.34) GAAMAPTCYP3A4USP2ALDH1A1
SCHEMBL25201693 0.85 CYP19A1 (0.30) ALDH1A1CYP19A1
SCHEMBL3751687 0.83
SCHEMBL3751684 0.83
SCHEMBL25197568 0.83 ALDH1A1 (0.35) GAAMAPTNPSR1TSHRALDH1A1
SCHEMBL25199449 0.82 USP2 (0.33) CYP3A4USP2CYP19A1PTGS1
SCHEMBL25200083 0.82 USP2 (0.33) CYP3A4USP2CYP19A1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4405323-B1 PROCESS FOR PREPARING A CYCLIC DIENE FIRMENICH & CIE (CH) 2026-01-14 EP disclosed
US-20250034074-A1 PROCESS FOR PREPARING A CYCLIC DIENE FIRMENICH SA (CH) 2025-01-30 US disclosed
EP-4405323-A1 PROCESS FOR PREPARING A CYCLIC DIENE Firmenich SA (CH) 2024-07-31 EP disclosed
WO-2023094502-A1 PROCESS FOR PREPARING A CYCLIC DIENE FIRMENICH SA (CH) 2023-06-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034074-A1 PROCESS FOR PREPARING A CYCLIC DIENE DHPS, FDFT1, CYP17A1 GAA 1479/4885MAPT 2999/4885NPSR1 3151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.