Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.78 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | BCL9 | O00512 | 11/20 | 0.67 |
| ▸ | CTNNB1 | P35222 | 11/20 | 0.67 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.59 |
| ▸ | TUBB | P07437 | 1/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.59 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.59 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988273 | 0.89 | ABCB1 (0.78) | ABCG2ABCB1KDM4EGAAMAPT | |
| 3,5,6,7,8,3',4'-Heptamethoxyflavone SCHEMBL29467229 | 0.88 | ABCG2 (1.00) | ABCG2ABCB1KDM4EGAAMAPT | |
| 3,5,6,7,8,3',4'-Heptamethoxyflavone SCHEMBL31621487 | 0.88 | ABCG2 (1.00) | ABCG2ABCB1KDM4EGAAMAPT | |
| 3,5,6,7,8,3',4'-Heptamethoxyflavone SCHEMBL1764676 | 0.88 | ABCG2 (1.00) | ABCG2ABCB1KDM4EGAAMAPT | |
| SCHEMBL29934461 | 0.86 | ADORA3 (0.64) | ABCG2ABCB1KDM4EGAAMAPT | |
| SCHEMBL19347141 | 0.83 | ABCG2 (0.72) | ABCG2ABCB1KDM4EGAAMAPT | |
| SCHEMBL1764425 | 0.83 | KDM4E (0.74) | ABCG2ABCB1KDM4EGAAMAPT | |
| SCHEMBL30819242 | 0.83 | KDM4E (0.74) | ABCG2ABCB1KDM4EGAAMAPT | |
| SCHEMBL1764666 | 0.83 | KDM4E (0.82) | ABCG2ABCB1KDM4EGAAMAPT | |
| SCHEMBL31511429 | 0.83 | KDM4E (0.82) | ABCG2ABCB1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023101420-A1 | COMPOSITION FOR PREVENTION OR TREATMENT OF OBESITY, FATTY LIVER, OR STEATOHEPATITIS COMPRISING MOMORDICA CHARANTIA EXTRACT OR HYDROFERULIC ACID DERIVED FROM MOMORDICA CHARANTIA AS ACTIVE INGREDIENT | 동아대학교 산학협력단 | 2023-06-08 | — | — | WO | disclosed |