Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.78 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.78 |
| ▸ | BCL9 | O00512 | 12/20 | 0.74 |
| ▸ | CTNNB1 | P35222 | 12/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.59 |
| ▸ | TUBB | P07437 | 2/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.59 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13445816 | 0.89 | KDM4E (0.68) | ABCB1ABCG2BCL9CTNNB1KDM4E | |
| SCHEMBL25221318 | 0.89 | ABCG2 (0.78) | ABCB1ABCG2BCL9CTNNB1KDM4E | |
| SCHEMBL16894627 | 0.89 | ADORA3 (0.64) | ABCB1ABCG2BCL9CTNNB1KDM4E | |
| SCHEMBL1764425 | 0.88 | KDM4E (0.74) | ABCB1ABCG2BCL9CTNNB1KDM4E | |
| SCHEMBL24895133 | 0.88 | KDM4E (0.67) | ABCB1ABCG2BCL9CTNNB1KDM4E | |
| SCHEMBL30819242 | 0.88 | KDM4E (0.74) | ABCB1ABCG2BCL9CTNNB1KDM4E | |
| 3,5,6,7,8,3',4'-Heptamethoxyflavone SCHEMBL1764676 | 0.88 | ABCG2 (1.00) | ABCB1ABCG2BCL9CTNNB1KDM4E | |
| 3,5,6,7,8,3',4'-Heptamethoxyflavone SCHEMBL29467229 | 0.88 | ABCG2 (1.00) | ABCB1ABCG2BCL9CTNNB1KDM4E | |
| 3,5,6,7,8,3',4'-Heptamethoxyflavone SCHEMBL31621487 | 0.88 | ABCG2 (1.00) | ABCB1ABCG2BCL9CTNNB1KDM4E | |
| SCHEMBL13464141 | 0.85 | ABCG2 (0.68) | ABCB1ABCG2BCL9CTNNB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2494874-B1 | Control of flavor characteristics of fruit juice | TROPICANA PROD INC (US) | 2013-12-11 | — | — | EP | claimed |
| EP-2494874-A1 | Control of flavor characteristics of fruit juice | TROPICANA PRODUCTS, INC. (US) | 2012-09-05 | — | — | EP | claimed |
| US-20060003947-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | THE CIT GROUP/CREDIT FINANCE, INC. | 2006-01-05 | — | — | US | claimed |
| US-20050249803-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | SOFT GEL TECHNOLOGIES, INC. | 2005-11-10 | — | — | US | claimed |
| EP-1278417-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK Synergie (CA) | 2003-01-29 | — | — | EP | claimed |
| WO-2001070029-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK SYNERGIE (CA) | 2001-09-27 | — | — | WO | claimed |
| EP-0605261-B1 | Use of a flavone derivative as taste modifier and a method of modifying taste | SAN EI GEN FFI INC (JP) | 1999-09-15 | — | — | EP | claimed |
| US-5580545-A | ADDING FLAVONE DERIVATIVES TO FOODS, BEVERAGES OR TOILETRIES TO ENHANCE OR REDUCE FLAVORS | SAN-EI GEN F.F.I., INC. (JP) | 1996-12-03 | — | — | US | claimed |
| US-20250011722-A1 | HEPATIC ORGANOIDS | KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) | 2025-01-09 | — | — | US | disclosed |
| CN-114984103-B | Orange peel extract and preparation method and application thereof | 赣南师范大学 | 2023-10-03 | — | — | CN | disclosed |
| WO-2023085931-A1 | HEPATIC ORGANOIDS | KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) | 2023-05-19 | — | — | WO | disclosed |
| CN-114984103-A | Orange peel extract and preparation method and application thereof | 赣南师范大学 | 2022-09-02 | — | — | CN | disclosed |
| US-10568924-B2 | Methods for the development of ortanique peel polymethoxylated flavones extract powder for commercial applications | UNIVERSITY OF THE WEST INDIES (JM) | 2020-02-25 | — | — | US | disclosed |
| US-9610276-B2 | Compositions and methods for glycemic control of subjects with impaired fasting glucose | KGK SYNERGIZE, INC. (CA) | 2017-04-04 | — | — | US | disclosed |
| US-20040214882-A1 | Compositions and methods of treating, reducing and preventing cardiovascular diseases and disorders with polymethoxyflavones | INTERHEALTH NUTRACEUTICALS INCORPORATED | 2004-10-28 | — | — | US | disclosed |
| EP-1278417-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK Synergie (CA) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001070029-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK SYNERGIE (CA) | 2001-09-27 | — | — | WO | disclosed |
| EP-0605261-B1 | Use of a flavone derivative as taste modifier and a method of modifying taste | SAN EI GEN FFI INC (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5580545-A | ADDING FLAVONE DERIVATIVES TO FOODS, BEVERAGES OR TOILETRIES TO ENHANCE OR REDUCE FLAVORS | SAN-EI GEN F.F.I., INC. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0605261-A2 | A taste modifier and a method of modifying taste | SAN-EI GEN F.F.I., INC. (JP) | 1994-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050249803-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | TTPA, CCNE2, PTGES | ABCB1 353/4885ABCG2 217/4885BCL9 2752/4885 |
| US-20060003947-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | TTPA, PLA2G10, GSTO1 | ABCB1 819/4885ABCG2 143/4885BCL9 2196/4885 |
| US-20040214882-A1 | Compositions and methods of treating, reducing and preventing cardiovascular diseases and disorders with polymethoxyflavones | TNNT2, PLIN3, TNNI3 | ABCB1 2647/4885ABCG2 1747/4885BCL9 3153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.