Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.73 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.73 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.67 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.67 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.65 |
| ▸ | TUBB | P07437 | 3/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.65 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.65 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.65 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.65 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.65 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.65 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.65 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30819242 | 1.00 | KDM4E (0.74) | KDM4EGAAMAPTABCB1ABCG2 | |
| Ternatin SCHEMBL1304220 | 0.93 | ALOX5 (0.71) | KDM4EGAAMAPTABCB1ABCG2 | |
| Ternatin SCHEMBL30731678 | 0.93 | ALOX5 (0.71) | KDM4EGAAMAPTABCB1ABCG2 | |
| SCHEMBL4649875 | 0.91 | MAPT (0.72) | KDM4EGAAMAPTABCB1ABCG2 | |
| SCHEMBL988273 | 0.88 | ABCB1 (0.78) | KDM4EGAAMAPTABCB1ABCG2 | |
| SCHEMBL21874496 | 0.88 | KDM4E (0.67) | KDM4EGAAMAPTABCB1ABCG2 | |
| SCHEMBL2344202 | 0.88 | CYP3A4 (0.65) | MAPTABCB1ABCG2ALOX5ABCC1 | |
| SCHEMBL13464139 | 0.87 | KDM4E (0.67) | KDM4EGAAMAPTABCB1ABCG2 | |
| SCHEMBL1764666 | 0.85 | KDM4E (0.82) | KDM4EGAAMAPTABCB1ABCG2 | |
| SCHEMBL507435 | 0.85 | MAPT (1.00) | KDM4EGAAMAPTABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669003-B2 | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs | JIN YONGRI (CN) | 2017-06-06 | — | — | US | claimed |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | JIN YONGRI (CN) | 2015-07-16 | — | — | US | claimed |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | WLLGEN, INC. (US) | 2014-02-06 | — | — | US | claimed |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | WELLGEN, INC. | 2007-11-29 | — | — | US | claimed |
| WO-2006132879-A2 | SOFT GEL CAPSULES CONTAINING POLYMETHOXYLATED FLAVONES AND PALM OIL TOCOTRIENOLS | SOFT GEL TECHNOLOGIES, INC. (US) | 2006-12-14 | — | — | WO | claimed |
| US-20060003947-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | THE CIT GROUP/CREDIT FINANCE, INC. | 2006-01-05 | — | — | US | claimed |
| US-20050249803-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | SOFT GEL TECHNOLOGIES, INC. | 2005-11-10 | — | — | US | claimed |
| EP-1278417-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK Synergie (CA) | 2003-01-29 | — | — | EP | claimed |
| WO-2001070029-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK SYNERGIE (CA) | 2001-09-27 | — | — | WO | claimed |
| US-20250090435-A1 | PRESERVATIVES FOR COSMETIC AND PHARMACEUTICAL COMPOSITIONS | SACHEM, INC. (US) | 2025-03-20 | — | — | US | disclosed |
| US-20250011722-A1 | HEPATIC ORGANOIDS | KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) | 2025-01-09 | — | — | US | disclosed |
| EP-4376798-A1 | PRESERVATIVES FOR COSMETIC AND PHARMACEUTICAL COMPOSITIONS | Sachem, Inc. (US) | 2024-06-05 | — | — | EP | disclosed |
| CN-117813075-A | Preservative for cosmetic and pharmaceutical compositions | 赛成公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2023085931-A1 | HEPATIC ORGANOIDS | KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) | 2023-05-19 | — | — | WO | disclosed |
| US-20040214882-A1 | Compositions and methods of treating, reducing and preventing cardiovascular diseases and disorders with polymethoxyflavones | INTERHEALTH NUTRACEUTICALS INCORPORATED | 2004-10-28 | — | — | US | disclosed |
| EP-1278417-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK Synergie (CA) | 2003-01-29 | — | — | EP | disclosed |
| EP-1119353-A4 | COMPOSITIONS AND METHODS OF INHIBITING NEOPLASTIC DISEASES WITH COMPOUNDS RELATED TO LIMOCITRIN AND 5-DESMETHYL SINENSETIN | KGK SYNERGIZE INC (CA) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001070029-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK SYNERGIE (CA) | 2001-09-27 | — | — | WO | disclosed |
| EP-1119353-A1 | COMPOSITIONS AND METHODS OF INHIBITING NEOPLASTIC DISEASES WITH COMPOUNDS RELATED TO LIMOCITRIN AND 5-DESMETHYL SINENSETIN | KGK Synergize Inc. (CA) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000019998-A1 | COMPOSITIONS AND METHODS OF INHIBITING NEOPLASTIC DISEASES WITH COMPOUNDS RELATED TO LIMOCITRIN AND 5-DESMETHYL SINENSETIN | KGK SYNERGIZE (CA) | 2000-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050249803-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | TTPA, CCNE2, PTGES | KDM4E 1084/4885GAA 3056/4885MAPT 1749/4885 |
| US-20250090435-A1 | PRESERVATIVES FOR COSMETIC AND PHARMACEUTICAL COMPOSITIONS | PLOD2, CUTA, PHOSPHO1 | KDM4E 3560/4885GAA 664/4885MAPT 1114/4885 |
| US-20060003947-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | TTPA, PLA2G10, GSTO1 | KDM4E 652/4885GAA 2851/4885MAPT 3282/4885 |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | PLIN5, FANCF, COXFA4 | KDM4E 1277/4885GAA 1679/4885MAPT 4329/4885 |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | CYP2D6, GATAD2A, CYP3A43 | KDM4E 437/4885GAA 2289/4885MAPT 1508/4885 |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | PLIN5, FANCF, COXFA4 | KDM4E 1277/4885GAA 1679/4885MAPT 4329/4885 |
| US-20040214882-A1 | Compositions and methods of treating, reducing and preventing cardiovascular diseases and disorders with polymethoxyflavones | TNNT2, PLIN3, TNNI3 | KDM4E 2659/4885GAA 1802/4885MAPT 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.