Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3157499 | 0.85 | ALDH1A1 (0.60) | TSHRALDH1A1TDP1CA2GABRA1 | |
| SCHEMBL872872 | 0.85 | GABRA1 (0.43) | TSHRALDH1A1TDP1CA2GABRA1 | |
| SCHEMBL17051291 | 0.85 | ALDH1A1 (0.38) | TSHRALDH1A1TDP1CA2TAAR1 | |
| SCHEMBL12317693 | 0.84 | CA2 (0.37) | TSHRALDH1A1TDP1CA2TAAR1 | |
| SCHEMBL5925963 | 0.84 | HTR2A (0.41) | TSHRALDH1A1TDP1HIF1A | |
| SCHEMBL27658469 | 0.84 | TSHR (0.37) | TSHRALDH1A1TDP1CA2TAAR1 | |
| SCHEMBL2139453 | 0.84 | KCNN4 (0.39) | TSHRALDH1A1TDP1CA2RIPK1 | |
| SCHEMBL7449086 | 0.84 | TSHR (0.37) | TSHRALDH1A1TDP1CA2TAAR1 | |
| SCHEMBL9743499 | 0.82 | CA2 (0.41) | TSHRALDH1A1TDP1CA2GABRA1 | |
| SCHEMBL18525388 | 0.82 | CA2 (0.41) | TSHRALDH1A1TDP1CA2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841479-B2 | Low monomer 1 : 1 monoadducts of reactive olefinic compounds and diisocyanates using insertable inhibitors | EVONIK DEGUSSA GMBH (DE) | 2014-09-23 | — | — | US | disclosed |
| US-20110251424-A1 | LOW MONOMER 1 : 1 MONOADDUCTS OF REACTIVE OLEFINIC COMPOUNDS AND DIISOCYANATES USING INSERTABLE INHIBITORS | EVONIK DEGUSSA GMBH (DE) | 2011-10-13 | — | — | US | disclosed |
| US-4069052-A | Color photographic materials with spiro heterocyclic stabilizing agents comprising 2-imidazolidine-4',5'-dione rings | AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) | 1978-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251424-A1 | LOW MONOMER 1 : 1 MONOADDUCTS OF REACTIVE OLEFINIC COMPOUNDS AND DIISOCYANATES USING INSERTABLE INHIBITORS | CYP1B1, HCFC1, DIMT1 | TSHR 4848/4885ALDH1A1 245/4885TDP1 282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.