SCHEMBL25222316

SCHEMBL25222316

O=P(O)(O)Oc1c(Cl)cccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 6/20 0.59
INPP5A Q14642 5/20 0.59
INPP5B P32019 2/20 0.59
AKT1 P31749 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.47
SRC P12931 6/20 0.46
KMT2A Q03164 1/20 0.44
LMNA P02545 1/20 0.41
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
USP2 O75604 1/20 0.38
HPGD P15428 1/20 0.38
PDE3A Q14432 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAPT P10636 1/20 0.38
PTK2B Q14289 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8332872 0.86 SMN1; SMN2 (0.47) INPPL1INPP5AINPP5BAKT1SMN1; SMN2
SCHEMBL7591865 0.86 INPPL1 (0.50) INPPL1INPP5AINPP5BAKT1SMN1; SMN2
SCHEMBL8329919 0.81 SMN1; SMN2 (0.43) INPPL1INPP5AINPP5BSMN1; SMN2KMT2A
SCHEMBL10483778 0.79 SMN1; SMN2 (0.42) INPPL1INPP5AINPP5BSMN1; SMN2KMT2A
SCHEMBL7775498 0.78 SMN1; SMN2 (0.40) INPPL1INPP5AINPP5BAKT1SMN1; SMN2
SCHEMBL25259132 0.77 INPPL1 (0.48) INPPL1INPP5AINPP5BAKT1SRC
SCHEMBL25222763 0.77 INPPL1 (0.53) INPPL1INPP5AINPP5BAKT1SMN1; SMN2
SCHEMBL557291 0.77 INPPL1 (0.59) INPPL1INPP5AINPP5BAKT1SMN1; SMN2
SCHEMBL8330707 0.77 SMN1; SMN2 (0.39) INPPL1INPP5AINPP5BAKT1SMN1; SMN2
SCHEMBL2127225 0.76 LMNA (0.64) INPPL1INPP5AINPP5BAKT1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230176481-A1 FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-06-08 US disclosed
CN-115398342-A Film-forming composition 日产化学株式会社 2022-11-25 CN disclosed