Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYBB | P04839 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30368172 | 0.84 | CA12 (0.46) | POLBPLAACA2CA9ALPG | |
| SCHEMBL17311212 | 0.84 | CA12 (0.46) | POLBPLAACA2CA9ALPG | |
| SCHEMBL28214996 | 0.75 | NPC1 (0.48) | PKMHTTALDH1A1HPGDPOLB | |
| SCHEMBL15394749 | 0.74 | PKM (0.62) | PKMCYBBHTTALDH1A1HPGD | |
| SCHEMBL27594954 | 0.74 | PKM (0.62) | PKMCYBBHTTALDH1A1HPGD | |
| SCHEMBL14357335 | 0.74 | PKM (0.68) | PKMCYBBHTTALDH1A1HPGD | |
| SCHEMBL469649 | 0.74 | PKM (0.62) | PKMCYBBHTTALDH1A1HPGD | |
| SCHEMBL30017193 | 0.74 | PKM (0.62) | PKMCYBBHTTALDH1A1HPGD | |
| SCHEMBL26922809 | 0.73 | KMO (0.47) | HTTALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL13977643 | 0.72 | PTPN1 (0.56) | PKMALDH1A1HPGDPOLBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097678-A1 | METHOD FOR SYNTHESIZING (R)-5-(2,2-DIMETHYL-4H-BENZO[D][1,3]DIOXIN-6-YL)OXAZOLIDIN-2-ONE | 广东莱佛士制药技术有限公司 | 2023-06-08 | — | — | WO | disclosed |